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Spontane Hämatomneigung und Hüftschmerzen bei einer 65-jährigen Patientin

Spontaneous hematoma and hip pain in a 65-year old patient

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Zusammenfassung

Wir berichten über eine 65-jährige Patientin mit erworbener Hemmkörperhämophilie. Die erworbene Hemmkörperhämophilie ist durch die Ausbildung von Antikörpern (Inhibitoren) gegen Gerinnungsfaktoren charakterisiert. Durch eine Beeinträchtigung der plasmatischen Gerinnung kommt es bei primär Gerinnungsgesunden zu einer schweren erworbenen Blutungsneigung mit potenziell tödlichem Verlauf. In der Diskussion wird auf die Pathophysiologie, Diagnostik und Therapie der Hemmkörperhämophilie eingegangen.

Abstract

The case of a 65-year-old woman with acquired hemophilia is reported. Acquired hemophilia is characterized by the development of inhibitors directed against coagulation factors. Impairment of plasmatic hemostasis leads to a severe bleeding tendency in individuals without a preexisting coagulation defect with considerable mortality. Pathophysiology, diagnostic work-up, and treatment are summarized and discussed.

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Authors and Affiliations

  1. LaboMed Gerinnungszentrum Berlin, Tauentzienstr. 7b/c, 10789, Berlin, Deutschland

    C. Sucker, S. Korfmacher & M. Papp-Váry

  2. Institut für Radiologie, Charité-Universitätsmedizin Berlin, Campus Virchow-Klinikum, Berlin, Deutschland

    C. Grieser

  3. Klinik für Hämatologie und Onkologie, Charité-Universitätsmedizin Berlin, Campus Virchow-Klinikum, Berlin, Deutschland

    H. Riess

Authors
  1. C. Sucker
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  2. S. Korfmacher
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  3. M. Papp-Váry
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  4. C. Grieser
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  5. H. Riess
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Correspondence to C. Sucker.

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Sucker, C., Korfmacher, S., Papp-Váry, M. et al. Spontane Hämatomneigung und Hüftschmerzen bei einer 65-jährigen Patientin. Internist 53, 1234–1239 (2012). https://doi.org/10.1007/s00108-012-3105-7

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  • DOI: https://doi.org/10.1007/s00108-012-3105-7

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