Zusammenfassung
Die schmerzlose, nebenwirkungsarme und nichtinvasive Anwendung von Silikon wird seit über 20 Jahren erfolgreich in der Therapie und Prävention hypertropher und keloider Narben eingesetzt. Die Auswertung der Patient Scar Assessment Scale zeigte in der durchgeführten Studie eine signifikant höhere Zufriedenheit der Patienten bezüglich der Silikonanwendung gegenüber der Placebotherapie nach 3-monatiger Anwendung. Nach Absetzen der Therapie konnte bei 3-monatiger Anwendung kein nachhaltiger, langfristiger Einfluss von Silikonspray auf das objektive Ergebnis der Narbenbildung beobachtet werden. Wegen der signifikanten Unterschiede hinsichtlich der Patientenzufriedenheit nach Therapieende und unter Berücksichtigung der sicheren und einfachen Anwendung sollte im Einzelfall geprüft werden, ob im Hinblick auf das psychische Wohlbefinden des Patienten und die therapiebegleitende temporäre Narbenverbesserung eine Behandlungsindikation vorliegt.
Abstract
For more than two decades silicone has successfully been employed in the treatment and prevention of hypertrophic scars and keloids as a painless noninvasive modality with few side effects. In the present trial, after 3 months of treatment the Patient Scar Assessment Scale demonstrated that patient satisfaction with the silicone application was significantly higher compared to placebo. When treatment was stopped after 3 months, the topical silicone spray did not exhibit any lasting long-term impact on the objective results of scar formation. Due to the significant differences in patient satisfaction once treatment has ended and since the administration is safe and simple, any final decision on treatment indication should be tailored to the patient and include the psychological well-being of the patient as well as the temporary improvement in scar formation during treatment.
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Stoffels, I., Wolter, T., Sailer, A. et al. Einfluss eines Silikonsprays auf die Narbenbildung. Hautarzt 61, 332–338 (2010). https://doi.org/10.1007/s00105-009-1886-y
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DOI: https://doi.org/10.1007/s00105-009-1886-y