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Elastolyse der mittleren Dermis

Mid-dermal elastolysis

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Zusammenfassung

Die Elastolyse der mittleren Dermis ist eine seltene Erkrankung bislang ungeklärter Ätiologie, die histologisch durch einen umschriebenen Verlust der elastischen Fasern im Bereich der mittleren Dermis gekennzeichnet ist. Klinisch ist die papulöse bis plaqueartige Fältelung der Haut typisch, inflammatorische und nichtentzündliche Formen wurden beschrieben. Berichtet wird über eine 39-jährige Patientin mit ausgedehnter Hautfältelung im Bereich des Stammes und der oberen Extremitäten nach extensiver UV-Lichtexposition unter Darstellung der klinischen und histopathologischen Befunde. Anhand des Fallberichtes werden die Differenzialdiagnosen diskutiert und eine Literaturübersicht gegeben.

Abstract

Mid-dermal elastolysis is a rare dermatosis of still unknown etiology with a characteristic mid-dermal loss of elastic tissue on histopatholoy. Papular and plaque-like wrinkling of the skin as well as inflammatory and non-inflammatory variants have been described. We present a 39-year-old patient with extended skin wrinkling of the trunk and upper extremities after extensive UV light exposure and describe the clinical and histopathological findings. Based on our case, differential diagnoses are discussed and the literature is reviewed.

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Helbig, D., Schlaak, M., Renner, R. et al. Elastolyse der mittleren Dermis. Hautarzt 61, 779–784 (2010). https://doi.org/10.1007/s00105-009-1883-1

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  • DOI: https://doi.org/10.1007/s00105-009-1883-1

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