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Inzidenz der Übertragung von Infektionserregern von einem Intensivpatienten zum anderen

Ergebnisse der SIR-3-Studie

Incidence of transmission of pathogens in intensive care units

Results of the SIR 3 study

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Zusammenfassung

Ziel dieser Studie war die Bestimmung der Inzidenz von Übertragungsereignissen von nosokomialen Infektionserregern und von transmissionsassoziierten nosokomialen Infektionen auf Intensivstationen. Dazu wurden in 5 Intensivstationen eines Universitätsklinikum über einen Zeitraum von 18 Monaten von allen Patienten mit mehr als 2-Tage-Aufenthaltszeit sowohl alle nosokomialen Infektionen erfasst als auch 10 der wichtigsten nosokomialen Infektionserreger (Indikatorspezies) gesammelt und typisiert. Insgesamt wurden im Laufe von 28.498 Patiententagen 431 nosokomiale Infektionen gefunden (Inzidenzdichte 15,1/1000 Patiententage); 278 von ihnen wurden durch einen Erreger der Indikatorspezies verursacht. Es wurden 141 Übertragungsereignisse ermittelt; die Inzidenz der Transmissionen betrug 5,0/1000 Patiententage. Von den nosokomialen Infektionen waren 41 transmissionsassoziiert, das entspricht einem Anteil von 14,5% aller nosokomialen Infektionen. Die Ergebnisse dieser Studie zeigen, dass auch in Intensivstationen mit mittleren nosokomialen Infektionsraten ein nicht zu vernachlässigender Anteil der Infektionen potenziell vermeidbar wäre.

Abstract

The objective of this study was to determine the incidence of episodes of transmission of nosocomial pathogens and of those pathogens leading to nosocomial infections. Over a period of 18 months all patients from 5 intensive care units (ICUs) who stayed for more than 2 days were included in this study. Surveillance of nosocomial infections was carried out and all isolates of 10 of the most frequent pathogens in ICUs (indicator pathogens) were collected and typed. A total of 28,498 patient days and 431 nosocomial infections were observed (incidence density 15.1 per 1,000 patient days), among them 278 caused by 1 of the selected indicator pathogens. A total of 141 episodes of transmissions were identified, corresponding to an incidence of episodes of transmision of 5.0 per 1,000 patient days and 41 nosocomial infections were transmission-associated, corresponding to 14.5% of all nosocomial infections. The data of this study demonstrate that even in ICUs with average nosocomial infection rates, some nosocomial infections could be avoided.

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Authors and Affiliations

  1. Institut für Hygiene und Umweltmedizin, Charité, Universitätsmedizin, Berlin

    S. Bärwolff, F. Schwab, M. Behnke, C. Geffers, K. Weist, K. Beilecke & H. Rüden

  2. National Institute for Public Health and the Environment (RIVM), Centre for Infectious Diseases Epidemiology, Bilthoven

    H. Grundmann

  3. London School of Hygiene and Tropical Medicine, London

    A. Tami

  4. Institut für Hygiene und Mikrobiologie, Charité, Universitätsmedizin, Berlin

    E. Halle, U. Göbel & R. Schiller

  5. Institut für Umweltmedizin und Krankenhaushygiene, Universitätsklinikum, Freiburg

    D. Jonas

  6. Robert Koch-Institut, Wernigerode

    I. Klare, W. Witte & E. Dinger

  7. Institut für Medizinische Mikrobiologie und Krankenhaushygiene, Medizinische Hochschule, Hannover

    P. Gastmeier

  8. Institut für Medizinische Mikrobiologie und Krankenhaushygiene, Medizinische Hochschule, Carl-Neuberg-Str. 1, 30625, Hannover

    P. Gastmeier

Authors
  1. S. Bärwolff
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  2. H. Grundmann
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  3. F. Schwab
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  4. A. Tami
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  5. M. Behnke
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  6. C. Geffers
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  7. E. Halle
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  8. U. Göbel
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  9. R. Schiller
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  10. D. Jonas
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  11. I. Klare
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  12. K. Weist
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  13. W. Witte
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  14. E. Dinger
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  15. K. Beilecke
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  16. H. Rüden
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  17. P. Gastmeier
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Corresponding author

Correspondence to P. Gastmeier.

Additional information

SIR: „spread of nosocomial infections and resistant pathogens“, 3. Teilprojekt des Infektionsepidemiologischen Netzwerkes des Bundesministeriums für Bildung und Forschung.

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Bärwolff, S., Grundmann, H., Schwab, F. et al. Inzidenz der Übertragung von Infektionserregern von einem Intensivpatienten zum anderen. Anaesthesist 54, 560–566 (2005). https://doi.org/10.1007/s00101-005-0848-8

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  • DOI: https://doi.org/10.1007/s00101-005-0848-8

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