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Central nervous system stem cells in the embryo and adult

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The central nervous system is generated from neural stem cells during embryonic development. These cells are multipotent and generate neurons, astrocytes and oligodendrocytes. The last few years it has been found that there are populations of stem cells also in the adult mammalian brain and spinal cord. In this paper, we review the recent development in the field of embryonic and adult neural stem cells.

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Received 26 March 1998; received after revision 27 April 1998; accepted 27 April 1998

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Frisén, J., Johansson, C., Lothian, C. et al. Central nervous system stem cells in the embryo and adult. CMLS, Cell. Mol. Life Sci. 54, 935–945 (1998). https://doi.org/10.1007/s000180050224

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  • DOI: https://doi.org/10.1007/s000180050224

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