Skip to main content
Log in

GPIIb/IIIa-Blockade zur Optimierung der Thrombolyse bei aktuem Myokardinfarkt

Herz Aims and scope Submit manuscript

Hintergrund:

Die thrombolytische Therapie ist eine etablierte Therapieform des akuten Myokardinfarkts.

GPIIb/IIIa-Blocker + moderne Thrombolytika: Der derzeit attraktivste Ansatz zur weiteren Optimierung der thrombolytischen Therapie ist der Einsatz von GPIIb/IIIa-Blockern in Kombination mit reduzierten Dosierugen von modernen Thrombolytika wie Alteplase und Reteplase. Die Übersichtsarbeit fasst die bisher vorliegenden Ergebnisse der klinischen Studien zusammen und unterstreicht ihre Bedeutung für die koronare Angioplastie im unmittelbaren Anschluss an die Thrombolyse.

Background:

Thrombolytic therapy is an established strategy for the treatment of acute myocardial infarction.

GPIIb/IIIa Blockers + Modern Thrombolytic Agents: At present, the most attractive development for optimizing thrombolytic therapy includes the use of GPIIb/IIIa blockers in combination with modern thrombolytic agents such as alteplase and reteplase. The review summarizes the available results of clinical studies using standard doses of trombolytic agents (TAMI 8, IMPACT-AMI, and PARADIGM) or reduced dosages of thrombolytic agents (TIMI 14 and SPEED) for combination therapy. The review also focuses on the implications of the combination therapy for coronary angioplasty immediately following coronary thrombolysis.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Author information

Authors and Affiliations

Authors

Additional information

Rights and permissions

Reprints and permissions

About this article

Cite this article

Nordt, T., Peter, K. & Bode, C. GPIIb/IIIa-Blockade zur Optimierung der Thrombolyse bei aktuem Myokardinfarkt. Herz 26 (Suppl 1), S42–S45 (2001). https://doi.org/10.1007/PL00014031

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1007/PL00014031

Navigation