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The Buffalo OsteoPerio Studies: Summary of Our Findings and the Unique Contributions of Robert J. Genco, DDS, PhD

  • Host Parasite Interactions in Periodontal Disease (C Genco and D Kinane, Section Editors)
  • Published:
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Abstract

Purpose of Review

Robert (“Bob”) Genco was a member of the research team that established the Buffalo Osteoporosis and Periodontal Disease (OsteoPerio) study. Here we detail the scientific discoveries emanating from this enduring collaboration.

Recent Findings

OsteoPerio is ancillary to the Women’s Health Initiative Observational Study (WHI-OS). WHI-OS is a longitudinal study of 93,676 postmenopausal women aged 50–79 enrolled at 40 US centers (enrolled in 1993–1998). OsteoPerio enrolled 1342 women 3 years later (1997–2001) from the Buffalo WHI-OS participants to study the association of osteoporosis and periodontal disease. OsteoPerio has 5-year (N = 1026) and 17-year (N = 518) follow-up examinations. In addition to information on health status from the WHI-OS, OsteoPerio further included comprehensive oral examinations assessing probing pocket depth, clinical attachment loss, gingival bleeding, alveolar crestal height, and decay/caries, missing, and filled teeth. Systemic bone density (measured by DXA), blood, saliva, and plaque also were collected at all three visits.

Summary

Findings from these studies are summarized here.

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Authors and Affiliations

  1. Department of Epidemiology and Environmental Health, School of Public Health and Health Professions, University at Buffalo, 410 Kimball Tower, Buffalo, NY, 14214, USA

    Jean Wactawski-Wende

  2. Department of Epidemiology and Environmental Health, School of Public Health and Health Professions, University at Buffalo, 270 Farber Hall, Buffalo, NY, 14214, USA

    Michael J. LaMonte, Kathy M. Hovey & Hailey R. Banack

Authors
  1. Jean Wactawski-Wende
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  2. Michael J. LaMonte
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  3. Kathy M. Hovey
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  4. Hailey R. Banack
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Correspondence to Jean Wactawski-Wende.

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This article is part of the Topical Collection on Host Parasite Interactions in Periodontal Disease

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Wactawski-Wende, J., LaMonte, M.J., Hovey, K.M. et al. The Buffalo OsteoPerio Studies: Summary of Our Findings and the Unique Contributions of Robert J. Genco, DDS, PhD. Curr Oral Health Rep 7, 29–36 (2020). https://doi.org/10.1007/s40496-020-00257-3

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  • DOI: https://doi.org/10.1007/s40496-020-00257-3

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