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Synthesis of tetrahydropyridines by one-pot multicomponent reaction using nano-sphere silica sulfuric acid

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Abstract

A highly efficient protocol for the synthesis of 1,2,3,4-tetrahydropyridines in the presence of nano-sphere silica sulfuric acid (NS-SSA) was used for good yields by one-pot multicomponent reaction (MCRs). The reagent nano-sphere silica sulfuric acid (NS-SSA) has several advantages, such as easy workup, nontoxicity, convenience and high yields of products.

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Acknowledgments

The authors acknowledge the Bu-Ali Sina University Research Council and Center of Excellence in Development of Environmentally Friendly Methods for Chemical Synthesis (CEDEFMCS) for providing support to this work.

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Authors and Affiliations

  1. Faculty of Chemistry, Bu-Ali Sina University, P.O. Box 6517838683, Hamedan, Iran

    Masoume Daraei, Mohammad Ali Zolfigol & Fateme Derakhshan-Panah

  2. Department of Chemistry Faculty of Science, Alzahra University, 1993893973, Vanak, Tehran, Iran

    Morteza Shiri

  3. Catalysis and Peptide Research Unit, School of Health Sciences, University of KwaZulu-Natal, Durban, 4001, South Africa

    Hendrik G. Kruger

  4. Pishro Parsian Company, 11th floor, No. 1917, Amir Bldg, above the four way the Jalal alahmad, North Kargar Ave, 1439713134, Tehran, Iran

    Mohammad Mokhlesi

Authors
  1. Masoume Daraei
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  2. Mohammad Ali Zolfigol
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  3. Fateme Derakhshan-Panah
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  4. Morteza Shiri
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  5. Hendrik G. Kruger
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  6. Mohammad Mokhlesi
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Correspondence to Mohammad Mokhlesi.

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Daraei, M., Zolfigol, M.A., Derakhshan-Panah, F. et al. Synthesis of tetrahydropyridines by one-pot multicomponent reaction using nano-sphere silica sulfuric acid. J IRAN CHEM SOC 12, 855–861 (2015). https://doi.org/10.1007/s13738-014-0548-x

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  • DOI: https://doi.org/10.1007/s13738-014-0548-x

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