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Review of techniques for diagnosis of catheter-related Candida biofilm infections

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Abstract

Recent evidence shows that many hospital-acquired infections, including most device-associated infections, involve the persistence of sessile organisms in the form of biofilms that are attached to a device surface and encased in an extracellular matrix. The cells in this environment exhibit an altered phenotype with respect to antimicrobial resistance and thus are extraordinarily difficult to eradicate without device removal. Although a number of implantable and topical devices are at risk for Candida biofilm formation, this review focuses on the diagnosis of the most common of these infections, biofilm growth on the surface of central venous catheters and urinary catheters.

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  1. Departments of Medicine and Medical Microbiology and Immunology, University of Wisconsin, 600 Highland Avenue Room H4.572, Madison, WI, 53792, USA

    David Andes

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  1. Jeniel E. Nett
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  2. David Andes
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Nett, J.E., Andes, D. Review of techniques for diagnosis of catheter-related Candida biofilm infections. Curr Fungal Infect Rep 2, 237–243 (2008). https://doi.org/10.1007/s12281-008-0035-x

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