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Obesity and the Overactive Bladder

  • Overactive Bladder (A Klausner, Section Editor)
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Abstract

Obesity (BMI greater than 30 kg.m-2) and overweight (BMI greater 25-30 kg.m-2) are associated with an increased prevalence of pelvic floor disorders, including urinary incontinence and overactive bladder (OAB) syndrome. A positive association between obesity and OAB is present in women, although it is more difficult to demonstrate in men. OAB may result from several obesity-related conditions including the mechanical effect of increased body mass on the bladder, a result of type-II diabetes or the presence of metabolic syndrome. The underlying metabolic defects of the latter two conditions in generating OAB are discussed. Finally the involvement of endothelial dysfunction as a cause of OAB is considered, as this pathology is a result of several obesity-related conditions.

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Acknowledgement

This article was written while the author was a member of an EU FP7 consortium, INComb.

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No potential conflicts of interest relevant to this article were reported.

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  1. The Institute of Biosciences and Medicine, University of Surrey, Guildford, GU2 7XH, UK

    C. H. Fry

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Fry, C.H. Obesity and the Overactive Bladder. Curr Bladder Dysfunct Rep 8, 62–68 (2013). https://doi.org/10.1007/s11884-012-0172-5

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