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Adiponectin and cardiovascular inflammatory responses

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Abstract

Obesity is recognized as a cause of many metabolic and cardiovascular disorders through its ability to promote chronic systemic inflammation. Recent studies have found that adipose tissues secrete numerous cytokines that are referred to as adipokines. Although most adipokines induce inflammation, adiponectin inhibits inflammatory reactions and protects against metabolic and cardiovascular diseases. This review focuses on the anti-inflammatory properties of adiponectin in various experimental systems, especially with respect to cardiovascular diseases.

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Authors and Affiliations

  1. Molecular Cardiology/Whitaker Cardiovascular Institute, Boston University School of Medicine, 715 Albany Street, W611, Boston, MA, 02118, USA

    Noriyuki Ouchi MD, PhD

Authors
  1. Yukihiro Takemura MD, PhD
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  2. Kenneth Walsh PhD
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  3. Noriyuki Ouchi MD, PhD
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Corresponding author

Correspondence to Noriyuki Ouchi MD, PhD.

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Takemura, Y., Walsh, K. & Ouchi, N. Adiponectin and cardiovascular inflammatory responses. Curr Atheroscler Rep 9, 238–243 (2007). https://doi.org/10.1007/s11883-007-0025-4

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  • DOI: https://doi.org/10.1007/s11883-007-0025-4

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