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Piezoelectric inkjet printing of medical adhesives and sealants

  • Biological and Biomedical Materials / Research Summary
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Abstract

Piezoelectric inkjet printing is a noncontact process that enables microscale processing of biological materials. In this research summary, the use of piezoelectric inkjet printing for patterning medical adhesives and sealants, including a two-component polyethylene glycol hydrogel-based medical sealant, an N-butyl cyanoacrylate tissue adhesive, and a mussel adhesive protein biological adhesive, is described The effect of Fe(III) on mussel adhesive protein structure was evaluated by means of atomic force microscopy. The ability to process microscale patterns of medical sealants and adhesives will provide an improvement in tissue joining, including enhanced tissue integrity, reduced bond lines, and decreased adhesive toxicity. Piezoelectric inkjet deposition of medical adhesives and sealants may be used in wound closure, fracture fixation, and microscale vascular surgery.

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Authors and Affiliations

  1. Joint Department of Biomedical Engineering, University of North Carolina and North Carolina State University, Raleigh, NC, 27695, USA

    Ryan D. Boehm, Shaun D. Gittard, Jacqueline M. H. Byrne, Anand Doraiswamy & Roger J. Narayan

  2. Department of Chemistry, Purdue University, West Lafayette, Indiana, 47907-2084, USA

    Jonathan J. Wilker & Timothy M. Dunaway

  3. Surface Science and Nano-Tribology Laboratory, Eastern Michigan University, Ypsilanti, MI, 48197, USA

    Rene Crombez & Weidian Shen

  4. Edward P. Fitts Department of Industrial and Systems Engineering, North Carolina State University, Raleigh, NC, 27695, USA

    Yuan-Shin Lee

Authors
  1. Ryan D. Boehm
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  2. Shaun D. Gittard
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  3. Jacqueline M. H. Byrne
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  4. Anand Doraiswamy
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  5. Jonathan J. Wilker
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  6. Timothy M. Dunaway
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  7. Rene Crombez
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  8. Weidian Shen
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  9. Yuan-Shin Lee
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  10. Roger J. Narayan
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Correspondence to Roger J. Narayan.

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Boehm, R.D., Gittard, S.D., Byrne, J.M.H. et al. Piezoelectric inkjet printing of medical adhesives and sealants. JOM 62, 56–60 (2010). https://doi.org/10.1007/s11837-010-0109-4

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  • DOI: https://doi.org/10.1007/s11837-010-0109-4

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