Skip to main content
Log in

Engineered nanoparticles circumvent the adaptive treatment tolerance to immune-checkpoint blockade therapy

  • Perspectives
  • Published:
Science China Chemistry Aims and scope Submit manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

References

  1. Gotwals P, Cameron S, Cipolletta D, Cremasco V, Crystal A, Hewes B, Mueller B, Quaratino S, Sabatos-Peyton C, Petruzzelli L, Engelman JA, Dranoff G. Nat Rev Cancer, 2017, 17: 286–301

    Article  CAS  Google Scholar 

  2. Keklikoglou I, Cianciaruso C, Güç E, Squadrito ML, Spring LM, Tazzyman S, Lambein L, Poissonnier A, Ferraro GB, Baer C, Cassará A, Guichard A, Iruela-Arispe ML, Lewis CE, Coussens LM, Bardia A, Jain RK, Pollard JW, De Palma M. Nat Cell Biol, 2019, 21: 190–202

    Article  CAS  Google Scholar 

  3. Wei SC, Duffy CR, Allison JP. Cancer Discov, 2018, 8: 1069–1086

    Article  Google Scholar 

  4. Gong N, Ma X, Ye X, Zhou Q, Chen X, Tan X, Yao S, Huo S, Zhang T, Chen S, Teng X, Hu X, Yu J, Gan Y, Jiang H, Li J, Liang XJ. Nat Nanotechnol, 2019, 14: 379–387

    Article  CAS  Google Scholar 

  5. Motevalli SM, Eltahan AS, Liu L, Magrini A, Rosato N, Guo W, Bottini M, Liang XJ. Biophys Rep, 2019, 5: 19–30

    Article  CAS  Google Scholar 

  6. Yarchoan M, Hopkins A, Jaffee EM. N Engl J Med, 2017, 377: 2500–2501

    Article  Google Scholar 

  7. Mathios D, Kim JE, Mangraviti A, Phallen J, Park CK, Jackson CM, Garzon-Muvdi T, Kim E, Theodros D, Polanczyk M, Martin AM, Suk I, Ye X, Tyler B, Bettegowda C, Brem H, Pardoll DM, Lim M. Sci Transi Med, 2016, 8: 370ral80

    Google Scholar 

  8. Min Y, Roche KC, Tian S, Eblan MJ, McKinnon KP, Caster JM, Chai S, Herring LE, Zhang L, Zhang T, DeSimone JM, Tepper JE, Vincent BG, Serody JS, Wang AZ. Nat Nanotech, 2017, 12: 877–882

    Article  CAS  Google Scholar 

  9. Chao Y, Xu L, Liang C, Feng L, Xu J, Dong Z, Tian L, Yi X, Yang K, Liu Z. Nat Biomed Eng, 2018, 2: 611–621

    Article  CAS  Google Scholar 

  10. Duan X, Chan C, Han W, Guo N, Weichselbaum RR, Lin W. Nat Commun, 2019, 10: 1899

    Article  Google Scholar 

  11. Lu K, He C, Guo N, Chan C, Ni K, Lan G, Tang H, Pelizzari C, Fu YX, Spiotto MT, Weichselbaum RR, Lin W. Nat Biomed Eng, 2018, 2: 600–610

    Article  CAS  Google Scholar 

  12. Cheung AS, Zhang DKY, Koshy ST, Mooney DJ. Nat Biotechnol, 2018, 36: 160–169

    Article  CAS  Google Scholar 

  13. Sharma P, Hu-Lieskovan S, Wargo JA, Ribas A. Cell, 2017, 168: 707–723

    Article  CAS  Google Scholar 

  14. Chen G, Huang AC, Zhang W, Zhang G, Wu M, Xu W, Yu Z, Yang J, Wang B, Sun H, Xia H, Man Q, Zhong W, Antelo LF, Wu B, Xiong X, Liu X, Guan L, Li T, Liu S, Yang R, Lu Y, Dong L, McGettigan S, Somasundaram R, Radhakrishnan R, Mills G, Lu Y, Kim J, Chen YH, Dong H, Zhao Y, Karakousis GC, Mitchell TC, Schuchter LM, Herlyn M, Wherry EJ, Xu X, Guo W. Nature, 2018, 560: 382–386

    Article  CAS  Google Scholar 

  15. Poggio M, Hu T, Pai CC, Chu B, Belair CD, Chang A, Montabana E, Lang UE, Fu Q, Fong L, Blelloch R. Cell, 2019, 177: 414–427.e13

    Article  CAS  Google Scholar 

  16. Zhang X, Wang J, Chen Z, Hu Q, Wang C, Yan J, Dotti G, Huang P, Gu Z. Nana Lett, 2018, 18: 5716–5725

    Article  CAS  Google Scholar 

  17. Wang C, Sun W, Ye Y, Hu Q, Bomba HN, Gu Z. Nat Biomed Eng, 2017, 1: 0011

    Article  CAS  Google Scholar 

  18. Zhang X, Wang C, Wang J, Hu Q, Langworthy B, Ye Y, Sun W, Lin J, Wang T, Fine J, Cheng H, Dotti G, Huang P, Gu Z. Adv Mater, 2018, 30: 1707112

    Article  Google Scholar 

  19. Yao H, Lan J, Li C, Shi H, Brosseau JP, Wang H, Lu H, Fang C, Zhang Y, Liang L, Zhou X, Wang C, Xue Y, Cui Y, Xu J. Nat Biomed Eng, 2019, 3: 306–317

    Article  CAS  Google Scholar 

  20. Wang D, Wang T, Liu J, Yu H, Jiao S, Feng B, Zhou F, Fu Y, Yin Q, Zhang P, Zhang Z, Zhou Z, Li Y. Nana Lett, 2016, 16: 5503–5513

    Article  CAS  Google Scholar 

  21. Agrawal S, Statkevich P, Bajaj G, Feng Y, Saeger S, Desai DD, Park JS, Waxman IM, Roy A, Gupta M. J Clin Pharmacol, 2017, 57: 394–400

    Article  CAS  Google Scholar 

  22. Mazor R, King EM, Onda M, Cuburu N, Addissie S, Crown D, Liu XF, Kishimoto TK, Pastan I. Proc Natl Acad Sci USA, 2018, 115: E733–E742

    Article  CAS  Google Scholar 

  23. Pitt JM, Vétizou M, Daillère R, Roberti MP, Yamazaki T, Routy B, Lepage P, Boneca IG, Chamaillard M, Kroemer G, Zitvogel L. Immunity, 2016, 44: 1255–1269

    Article  CAS  Google Scholar 

Download references

Acknowledgments

We appreciate Prof. Massimo Bottini from University of Rome Tor Vergata, who provided many thoughtful suggestions and kind edit to our manuscript. This work was partially supported by the National Natural Science Foundation of China (31630027, 31430031, 81601603), the National Distinguished Young Scholars Grant (31225009), the NSFC-DFG Project (31761133013), and the External Cooperation Program of the Chinese Academy of Sciences (121D11KYSB20160066).

Author information

Authors and Affiliations

Authors

Corresponding authors

Correspondence to Weisheng Guo or Xing-Jie Liang.

Additional information

Conflict of interest

The authors declare that they have no conflict of interest.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Guo, W., Liu, L., Xiang, C. et al. Engineered nanoparticles circumvent the adaptive treatment tolerance to immune-checkpoint blockade therapy. Sci. China Chem. 62, 1557–1560 (2019). https://doi.org/10.1007/s11426-019-9588-4

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s11426-019-9588-4

Navigation