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Directing group-assisted transition-metal-catalyzed vinylic C-H bond functionalization

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Abstract

Transition-metal-catalyzed C-H bond activation represents one of the most attractive research areas in organic synthesis. In contrast to the great developments made in directed C-H bond functionalization of arenes, the directing group-assisted activation of non-aromatic vinylic C-H bonds still remains challenging. During the recent years, significant progress has been made in this fascinating field with various functionalized alkenes, heterocycles and carbocycles being obtained. This article will focus on the recent achievements in the field of directing-group-assisted vinylic C-H bond functionalization.

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Authors and Affiliations

  1. Beijing National Laboratory of Molecular Sciences (BNLMS); Key Laboratory of Bioorganic Chemistry and Molecular Engineering of Ministry of Education; College of Chemistry, Peking University, Beijing, 100871, China

    Kang Wang, Fangdong Hu, Yan Zhang & Jianbo Wang

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  1. Kang Wang
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  2. Fangdong Hu
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Correspondence to Jianbo Wang.

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Wang, K., Hu, F., Zhang, Y. et al. Directing group-assisted transition-metal-catalyzed vinylic C-H bond functionalization. Sci. China Chem. 58, 1252–1265 (2015). https://doi.org/10.1007/s11426-015-5362-5

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