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Rigenolides D–H, norsecoiridoid and secoiridoids from Gentiana rigescens Franch

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Abstract

Five new compounds, rigenolides D–H (1–5), were isolated from the aerial parts of Gentiana rigescens Franch. Their structures were assigned by detailed spectroscopic analyses and chemical conversions. Rigenolides D (1) and E (2) were elucidated to be a secoiridoid and a norsecoiridoid, respectively, possessing a dienone moiety in common. Rigenolides F–H (3–5) were assigned as acylated secoiridoid glucosides.

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Acknowledgements

This work was partly supported by JSPS KAKENHI Grant numbers JP18406028 and JP17K08337.

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Authors and Affiliations

  1. Graduate School of Pharmaceutical Sciences, Tokushima University, Tokushima, 770-8505, Japan

    Yoshihiro Suyama, Naonobu Tanaka & Yoshiki Kashiwada

  2. Graduate School of Technology, Industrial and Social Sciences, Tokushima University, Tokushima, 770-8513, Japan

    Naonobu Tanaka

  3. School of Pharmacy, Showa University, Shinagawa, 142-8555, Japan

    Kazuyoshi Kawazoe

  4. Faculty of Pharmaceutical Sciences, Sojo University, Kumamoto, 862-0082, Japan

    Kotaro Murakami

  5. State Key Laboratory of Phytochemistry and Plant Resources in West China, Kumming Institute of Botany, Chinese Academy of Sciences, Kumming, 650201, China

    Shun-Lin Li & Han-Dong Sun

Authors
  1. Yoshihiro Suyama
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  2. Naonobu Tanaka
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  3. Kazuyoshi Kawazoe
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  4. Kotaro Murakami
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  5. Shun-Lin Li
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  6. Han-Dong Sun
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  7. Yoshiki Kashiwada
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Corresponding author

Correspondence to Yoshiki Kashiwada.

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Suyama, Y., Tanaka, N., Kawazoe, K. et al. Rigenolides D–H, norsecoiridoid and secoiridoids from Gentiana rigescens Franch. J Nat Med 72, 576–581 (2018). https://doi.org/10.1007/s11418-018-1181-2

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  • DOI: https://doi.org/10.1007/s11418-018-1181-2

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