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Circadian preference in bipolar disorder

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Abstract

Purpose

A role for circadian rhythm abnormalities in the pathogenesis of bipolar disorder (BD) has been suggested. The present study assessed circadian preference, a subjective preference for activities in the morning or evening related to chronotype.

Methods

The sample was comprised of 81 outpatients with BD in remission and 79 control subjects. Circadian preference was derived from an interview evaluating biological rhythms and sleep pattern from the Pittsburgh Sleep Quality Index.

Results

Patients were significantly more likely to have an evening preference than control subjects. Circadian preference was also associated with sleep latency.

Conclusions

The association of evening preference and longer sleep latency may be related to the frequent clinical observation of a sleep/wake cycle reversal in bipolar disorder.

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References

  1. Leibenluft E, Suppes T (1999) Treating bipolar illness: focus on treatment algorithms and management of the sleep-wake cycle. Am J Psychiatry 156:1976–1981

    CAS  PubMed  Google Scholar 

  2. Jang KL, Lam RW, Livesley WJ, Vernon PA (1997) Gender differences in the heritability of seasonal mood change. Psychiatry Res 70:145–154

    Article  CAS  PubMed  Google Scholar 

  3. Horne JA, Ostberg O (1976) A self-assessment questionnaire to determine morningness-eveningness in human circadian rhythms. Int J Chronobiol 4:97–110

    CAS  PubMed  Google Scholar 

  4. Kerkhol GA (1985) Inter-individual differences in the human circadian system: a review. Biol Psychol 20:83–112

    Article  Google Scholar 

  5. Dijk DJ, von Schantz M (2005) Timing and consolidation of human sleep, wakefulness, and performance by a symphony of oscillators. J Biol Rhythms 20(4):279–290

    Article  PubMed  Google Scholar 

  6. Harvey AG (2008) Sleep and circadian rhythms in bipolar disorder: seeking synchrony, harmony, and regulation. Am J Psychiatry 165(7):820–829

    Article  PubMed  Google Scholar 

  7. Giglio LM, Andreazza AC, Andersen M et al (2009) Sleep in bipolar patients. Sleep Breath 13(2):169–173

    Article  PubMed  Google Scholar 

  8. Giglio LM, Magalhães PV, Andreazza AC et al. Development and use of a biological rhythm interview. J Affect Dis 118(1-3):161–165

  9. Giglio LM, Magalhaes PV, Kapczinski NS, Walz JC, Kapczinski F. Functional impact of biological rhythm disturbance in bipolar disorder. J Psychiatr Res (in press).

  10. Mansour HA, Wood J, Chowdari KV et al (2005) Circadian phase variation in bipolar I disorder. Chronobiol Int 22(3):571–584

    Article  PubMed  Google Scholar 

  11. Buysse DJ, Reynolds CF 3rd, Monk TH, Berman SR, Kupfer DJ (1989) The Pittsburgh sleep quality index: a new instrument for psychiatric practice and research. Psychiatry Res 28(2):193–213

    Article  CAS  PubMed  Google Scholar 

  12. Fleck MP, Guelfi JD, Poirier-Littré MF, Lôo H (1994) Application of a structured interview guide adapted to 4 depression scales. Encephale 20(5):479–486

    CAS  PubMed  Google Scholar 

  13. Vilela JÁ, Crippa JÁ, Del-Bem CM, Loureiro SR (2005) Reliability and validity of a Portuguese version of the young mania rating scale. Braz J Med Biol Res 38(9):1429–1439

    Article  CAS  PubMed  Google Scholar 

  14. Ahn YM, Chang J, Joo YH, Kim SC, Lee KY, Kim YS (2008) Chronotype distribuition in bipolar I disorder and schizophrenia in a Korean sample. Bipolar Disord 10:271–275

    Article  PubMed  Google Scholar 

  15. Hakkarainen R, Johansson C, Kieseppä T et al (2003) Seasonal changes, sleep length and circadian preference among twins with bipolar disorder. BMC Psychiatry 3:6

    Article  PubMed  Google Scholar 

  16. Hätönen T, Forsblom S, Kieseppä T, Lönnqvist J, Partonen T (2008) Circadian phenotype in patients with the co-morbid alcohol use and bipolar disorders. Alcohol Alcohol 43(5):564–568

    PubMed  Google Scholar 

  17. Lamont EW, Legault-Coutu D, Cermakian N, Boivin DB (2007) The role of circadian clock genes in mental disorder. Dialogues Clin Neurosci 9(3):333–342

    PubMed  Google Scholar 

  18. Gaina A, Sekine M, Kanayama H et al (2006) Morning-evening preference: sleep pattern spectrum and lifestyle habits among Japanese junior high school pupils. Chronobiol Int 23(3):607–621

    Article  PubMed  Google Scholar 

  19. Lehnkering H, Siegmund R (2007) Influence of chronotype, season, and sex of subject on sleep behavior of young adults. Chronobiol Int 24(5):875–888

    Article  PubMed  Google Scholar 

  20. Frank E, Swartz HA, Kupfer DJ (2000) Interpersonal and social rhythm therapy: managing the chaos of bipolar disorder. Biol Psychiatry 48(6):593–604

    Article  CAS  PubMed  Google Scholar 

Download references

Acknowledgments

Drs. Giglio and Magalhães are supported by doctoral scholarships from Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES), Brazil. Dr. Kapczinski has received grant/research support from Astra-Zeneca, Eli Lilly, the Janssen-Cilag, Servier, CNPq, CAPES, NARSAD and the Stanley Medical Research Institute; has been a member of the speakers’ boards for Astra-Zeneca, Eli Lilly, Janssen and Servier; and has served as a consultant for Servier. The other authors declare they have no conflict of interest in the matter.

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Authors and Affiliations

  1. Molecular Psychiatry Laboratory and INCT Translational Medicine, Hospital de Clínicas de Porto Alegre, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil

    Larriany Maria Falsin Giglio, Pedro V. S. Magalhães, Julio Cesar Walz, Lourenço Jakobson & Flávio Kapczinski

  2. Department of Psychobiology, Department of Pharmacology, Universidade Federal de São Paulo, São Paulo, Brazil

    Mônica Levy Andersen

  3. Departament of Physiology, Universidade Federal do Rio Grande do Norte, Rio Grande do Norte, Brazil

    Mônica Levy Andersen

  4. Laboratório de Psiquiatria Molecular, Hospital de Clinicas de Porto Alegre, Ramiro Barcelos, 2350, CEP 90035-003, Porto Alegre, Rio Grande do Sul, Brazil

    Flávio Kapczinski

Authors
  1. Larriany Maria Falsin Giglio
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  2. Pedro V. S. Magalhães
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  3. Mônica Levy Andersen
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  4. Julio Cesar Walz
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  5. Lourenço Jakobson
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  6. Flávio Kapczinski
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Corresponding author

Correspondence to Flávio Kapczinski.

Additional information

Funding sources: this study was supported by FIPE-HCPA

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Giglio, L.M.F., Magalhães, P.V.S., Andersen, M.L. et al. Circadian preference in bipolar disorder. Sleep Breath 14, 153–155 (2010). https://doi.org/10.1007/s11325-009-0301-3

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  • DOI: https://doi.org/10.1007/s11325-009-0301-3

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