Abstract
Caprine brucellosis is a bacterial zoonotic infection affecting goats especially in developing countries all over the world. In Malaysia, the risk factors associated with this infection in farms have not been studied. A case–control study was carried out in goat farms in four states of Malaysia to elucidate the risk factors associated with the infection on the farms using structured questionnaires and face-to-face interviews. Results indicate that the introduction of new animals (OR = 5.25; 90 % CI = 1.46, 18.88), younger age category of farms (OR = 5.53; 90 % CI = 1.09, 21.66), and farms with single breed of goats (OR = 8.50; 90 % CI = 1.27, 41.97) were significant risk factors for brucellosis. In order to control brucellosis or possibly eradicate it in goat farms, these factors need to be dealt with. Enforcing stringent importation protocols or complete ban of goat importation from brucellosis endemic countries will help reduce risk of introducing new infection into the country.
Similar content being viewed by others
References
Adamu, M., Mshelia, G.D., Adamu, N. and Ouda, L., 2012. Studies on farmer awareness on caprine abortion and the presence of Brucella abortus and Brucella melitensis in selected flocks in an arid zone of Nigeria, Journal of Veterinary Medicine and Animal Health, 4, 17-21.
Anon, 2012. Malaysia2012. Wikipedia.
Azevedo, S.S., Ferreira Neto, J.S., Dias, R.A., Ferreira, F., Amaku, M., Figueiredo, V.C.F., Lôbo, J.R., Gonçalves, V.S.P., Souza, A.C. and Vasconcellos, S.A., 2009. Situação epidemiológica da brucelose bovina no Estado do Espírito Santo [Epidemiological situation of bovine brucellosis in the State of Espírito Santo, Brazil], Arquivo Brasileiro de Medicina Veterinária e Zootecnia, 61, 19-26.
Aziz, A.J., Nor Shahidah, K., Chua, K.B. and Shamshad, S., 2012. Emerging Infectious Diseases - A Malaysian Perspective, OIE World Organisation for Animal health Workshop: Regional Representation for Asia and the Pacific.
Bamaiyi, P.H., Hassan, L., Khairani-Bejo, S., Zainal, M.A., Ramlan, M., Krishnan, N., Adzhar, A., Abdullah, N., Hamidah, N.H.M., Norsuhanna, M.M. and Hashim, S.N., 2012. Isolation and Molecular Characterization of Brucella melitensis from Seropositive Goats in Peninsula Malaysia, Tropical Biomedicine, 29, 513-518.
Bamaiyi, P.H., Hassan, L., Khairani-Bejo, S. and Zainal, M.A., 2014. Updates on brucellosis in Malaysia and southeast Asia, Malaysian Journal of Veterinary Research, 5, 71-82.
Bonfoh, B., Kasymbekov, J., Dürr, S., Toktobaev, N., Doherr, M., Schueth, T., Zinsstag, J. and Schelling, E., 2012. Representative Seroprevalences of Brucellosis in Humans and Livestock in Kyrgyzstan, EcoHealth, 9, 132-138.
Bunnell, T., 2004. Malaysia, modernity and the multimedia super corridor: a critical geography of intelligent landscapes, Vol. 4. Routledge.
Coelho, A., Coelho, A.C., Roboredo, M. and Rodrigues, J., 2007. A case control study of risk factors for brucellosis seropositivity in Portuguese small ruminants herds, Preventive Veterinary Medicine, 82, 291-301.
Coelho, A., Coelho, A.C., Góis, J., Pinto, M.d.L. and Rodrigues, J., 2008. Multifactorial correspondence analysis of risk factors for sheep and goat brucellosis seroprevalence, Small Ruminant Research, 78, 181-185.
Currò, V., Marineo, S., Vicari, D., Galuppo, L., Galluzzo, P., Nifosì, D., Pugliese, M., Migliazzo, A., Torina, A. and Caracappa, S., 2012. The isolation of Brucella spp. from sheep and goat farms in Sicily, Small Ruminant Research, 106, Supplement, S2-S5.
DVS, 2010. Brucella melitensis Veterinary Protocol Malaysia. In: Department of Veterinary Services MoAaA-BI, Malaysia (ed) PVM 1(5): 1/2010. Department of Veterinary Services, Putrajaya, Malaysia, Putrajaya. pp. 1-21.
Field, A., 2009. Exploring Statistics Using SPSS, Vol. SAGE publications, London.
Islam, M.A., Khatun, M.M., Werre, S.R., Sriranganathan, N. and Boyle, S.M., 2013. A review of Brucella seroprevalence among humans and animals in Bangladesh with special emphasis on epidemiology, risk factors and control opportunities, Veterinary Microbiology, 166, 317-326.
Lopes, L.B., Nicolino, R. and Haddad, J.P.A., 2010. Brucellosis - Risk Factors and Prevalence: A Review, The Open Veterinary Science Journal, 4, 72-84.
McCauley, L.M., Lancaster, M.J., Young, P., Butler, K.L. and Ainsworth, C.G., 2007. Comparison of ELISA and CFT assays for Chlamydophila abortus antibodies in ovine sera, Australian Veterinary Journal, 85, 325-328.
Mikolon, A.B., Gardner, I.A., Hernandez De Anda, J. and Hietala, S.K., 1998. Risk factors for brucellosis seropositivity of goat herds in the Mexicali Valley of Baja California, Mexico, Preventive Veterinary Medicine, 37, 185-195.
OIE, 2009. Caprine and Ovine Brucellosis (Excluding Brucella ovis), In: OIE (ed). Manual of Diagnostic Tests and Vaccines for Terrestrial Animals 2009, Vol. OIE-World Organization for Animal Health. pp. 2-8.
Rahman, A.K.M.A., Saegerman, C., Berkvens, D., Fretin, D., Gani, M.O., Ershaduzzaman, M., Ahmed, M.U. and Emmanuel, A., 2013. Bayesian estimation of true prevalence, sensitivity and specificity of indirect ELISA, Rose Bengal Test and Slow Agglutination Test for the diagnosis of brucellosis in sheep and goats in Bangladesh, Preventive Veterinary Medicine, 110, 242-252.
Refai, M., 2002. Incidence and control of brucellosis in the Near East region, Veterinary Microbiology, 90, 81-110.
Salata, R.A., 2012. 318 - Brucellosis, In. Goldman's Cecil Medicine (Twenty-Fourth Edition), Vol. W.B. Saunders, Philadelphia. pp. 1891-1893.
Seleem, M.N., Boyle, S.M. and Sriranganathan, N., 2010. Brucellosis: A re-emerging zoonosis, Veterinary Microbiology, 140, 392-398.
Sofian, M., Aghakhani, A., Velayati, A.A., Banifazl, M., Eslamifar, A. and Ramezani, A., 2008. Risk factors for human brucellosis in Iran: a case-control study, International Journal of Infectious Diseases, 12, 157-161.
Sulima, M. and Venkataraman, K.S., 2010. Economic Losses Due to Brucella melitensis Infection in Sheep and Goats, Tamilnadu Journal of Veterinary and Animal Sciences, 6, 191-192.
Sullivan, K.M., Dean, A. and Soe, M.M., 2009. OpenEpi: a web-based epidemiologic and statistical calculator for public health, Public Health Reports, 124, 471-474.
Teklue, T., Tolosa, T., Tuli, G., Beyene, B. and Hailu, B., 2013. Sero-prevalence and risk factors study of brucellosis in small ruminants in Southern Zone of Tigray Region, Northern Ethiopia, Tropical Animal Health and Production, 45, 1809-1815.
Vu, T., 2007. Rethinking the Traditional Concept of Livestock Services: A Study of Response Capacity in Thailand, Malaysia and Vietnam, Pro-Poor Livestock Policy Initiative, 41, 1-60.
Acknowledgments
The authors wish to acknowledge all the staff of the Department of Veterinary Services of Malaysia at state and district levels for their cooperation and untiring efforts towards the success of this study. The farmers are acknowledged for their patience and cooperation.
Conflict of interest
The authors declare that they have no conflict of interest.
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Bamaiyi, P.H., Hassan, L., Khairani-Bejo, S. et al. Case–control study on risk factors associated with Brucella Melitensis in goat farms in Peninsular Malaysia. Trop Anim Health Prod 46, 739–745 (2014). https://doi.org/10.1007/s11250-014-0557-x
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s11250-014-0557-x