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BRAF V600E mutation is a useful marker for differentiating Rathke’s cleft cyst with squamous metaplasia from papillary craniopharyngioma

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References

  1. Zada G, Lin N, Ojerholm E, Ramkissoon S, Laws ER (2010) Craniopharyngioma and other cystic epithelial lesions of the sellar region: a review of clinical, imaging, and histopathological relationships. Neurosurg Focus 28(4):E4

    Article  PubMed  Google Scholar 

  2. Brastianos PK, Taylor-Weiner A, Manley PE, Jones RT, Dias-Santagata D, Thorner AR, Lawrence MS, Rodriguez FJ, Bernardo LA, Schubert L, Sunkavalli A, Shillingford N, Calicchio ML, Lidov HG, Taha H, Martinez-Lage M, Santi M, Storm PB, Lee JY, Palmer JN, Adappa ND, Scott RM, Dunn IF, Laws ER Jr, Stewart C, Ligon KL, Hoang MP, Van Hummelen P, Hahn WC, Louis DN, Resnick AC, Kieran MW, Getz G, Santagata S (2014) Exome sequencing identifies BRAF mutations in papillary craniopharyngiomas. Nat Genet 46(2):161–165

    Article  PubMed Central  CAS  PubMed  Google Scholar 

  3. Singer G, Oldt R 3rd, Cohen Y, Wang BG, Sidransky D, Kurman RJ, Shih Ie M (2003) Mutations in BRAF and KRAS characterize the development of low-grade ovarian serous carcinoma. J Natl Cancer Inst 95(6):484–486

    Article  CAS  PubMed  Google Scholar 

  4. Lee ST, Kim JY, Kown MJ, Kim SW, Chung JH, Ahn MJ, Oh YL, Kim JW, Ki CS (2011) Mutant enrichment with 3’-modified oligonucleotides a practical PCR method for detecting trace mutant DNAs. J Mol Diagn 13(6):657–668

    Article  PubMed Central  CAS  PubMed  Google Scholar 

  5. Jones RT, Abedalthagafi MS, Brahmandam M, Greenfield EA, Hoang MP, Louis DN, Hornick JL, Santagata S (2014) Cross-reactivity of the BRAF VE1 antibody with epitopes in axonemal dyneins leads to staining of cilia. Mod Pathol. doi:10.1038/modpathol.2014.150

    Google Scholar 

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Acknowledgments

This study was funded by the National Research Foundation of Korea (NRF-2012R1A1A2004721) to Jang-Hee Kim.

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Authors declare that they have no conflicts of interest.

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All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards. For this type of study, formal consent is not required.

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Correspondence to Jang-Hee Kim.

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Kim, JH., Paulus, W. & Heim, S. BRAF V600E mutation is a useful marker for differentiating Rathke’s cleft cyst with squamous metaplasia from papillary craniopharyngioma. J Neurooncol 123, 189–191 (2015). https://doi.org/10.1007/s11060-015-1757-6

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  • DOI: https://doi.org/10.1007/s11060-015-1757-6

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