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Development of a method for high LET irradiation of liquid systems

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Abstract

A variety of processes, from material sterilization and cancer treatment to used nuclear fuel recycling, benefit from quantifying the sensitivity of the system to radiation. Determining the effects of alpha irradiation on a system may be of complementary interest to the effects of gamma irradiation, as alpha radiation has higher linear energy transfer (LET) and will likely result in different chemical damage effects. This becomes important in advanced nuclear fuel cycle processes where the radioactive materials to be handled in solutions contain significant amounts of alpha emitters. Here we describe a method for studying high LET radiation in a liquid system using a TRIGA® reactor and the 10B(n,α)7Li reaction. By fitting a model based on neutron diffusion and absorption to experimentally obtained Fricke dosimetry data, the high LET dose to a sample was predictable over the full range of reactor power available and varying 10B concentration. This method may be applied to study the effects of high LET radiation on any liquid system as long as a suitable molecule containing boron is used and appropriate neutron diffusion coefficients are known. A wide range of high LET dose rates from <10 Gy/h to >1,000 kGy/h may be obtained with this method.

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References

  1. Masuda T, Hatakeyama Y, Sunohara T (2005) Hollow fiber blood-processing device and method for packaging and sterilizing using a deoxidizer and radiation. U.S. Pat. Appl. Publ. US 20050063859 A1 20050324

  2. Basly JP, Duroux JL, Bernard M (1996) Gamma irradiation sterilization of orciprenaline and fenoterol. Int J Pharm 142(1):125–128

    Article  CAS  Google Scholar 

  3. Pascaud RS, Evans WT, McCullagh PJJ, FitzPatrick DP (1997) Influence of gamma-irradiation sterilization and temperature on the fracture toughness of ultra high-molecular-weight polyethylene. Biomaterials 18(10):727–735

    Article  CAS  Google Scholar 

  4. Razavi B, Song W, Santoke H, Cooper WJ (2011) Treatment of statin compounds by advanced oxidation processes: kinetic considerations and destruction mechanisms. Radiat Phys Chem 80(3):453–461

    Article  CAS  Google Scholar 

  5. Azar F, Yang HB, Venault L, Faure S (2012) Stability of water-soluble dyes under alpha and gamma radiation. Proceedings ATALANTE 2012—Nuclear Chemistry for sustainable fuel cycles, Montpolier, France, 2–7 Sep 2012

  6. Holland JP, Merklin JF, Razvi J (1978) The radiolysis of dodecane-tributyl phosphate solutions. Nucl Instrum Methods 153:589–593

    Article  CAS  Google Scholar 

  7. Mincher BJ, Modolo G, Mezyk SP (2009) Review article: the effects of radiation chemistry on solvent extraction: 1. Conditions in acidic solution and a review of TBP radiolysis. Solvent Extr Ion Exch 27:1–25

    Article  CAS  Google Scholar 

  8. Fermvik A, Gruner B, Kvicalova M, Ekberg C (2011) Semi-quantitative and quantitative studies on the gamma radiolysis of C5-BTBP. Radiochim Acta 99:113–119

    Article  CAS  Google Scholar 

  9. Choppin G, Liljenzin J, Rydberg J (2002) Radiochemistry and nuclear chemistry. Butterworth-Heinemann, Woburn

    Google Scholar 

  10. McDonell WR, Hart EJ (1954) Oxidation of aqueous ferrous sulfate solutions by charged particle radiations. J Am Chem Soc 76:2121–2124

    Article  CAS  Google Scholar 

  11. Sugo Y, Taguchi M, Sasaki Y, Hirota K, Kimura T (2009) Radiolysis study of actinide complexing agent by irradiation with helium ion beam. Radiat Phys Chem 78:1140–1144

    Article  CAS  Google Scholar 

  12. LaVerne JA, Enomoto K, Araos MS (2001) Heavy ion radiolysis of organic materials. Radiat Phys Chem 60:253–257

    Article  CAS  Google Scholar 

  13. Ladrielle T, Wanet P, Lemaire D, Apers DJ (1983) Alpha and gamma induced radiolysis of tributyl phosphate. Radiochem Radioanal Lett 59:355–364

    CAS  Google Scholar 

  14. Lloyd MH,Fellows RL (1985) Alpha radiolysis and other factors affecting hydrolysis of tributyl phoshpate. In: Report ORNL TM-9565; Order No. DE85015071, Oak Ridge National Laboratory

  15. Pearson J, Jan O, Miller GE, Nilsson M (2012) Studies of high linear energy transfer dosimetry by 10B(n, α)7Li reactions in aqueous and organic solvents. J Radioanal Nucl Chem 292:719–727

    Article  CAS  Google Scholar 

  16. Schuler RH, Barr NF (1956) Oxidation of ferrous sulfate by ionizing radiations from (n,α) reactions of boron and lithium. J Am Chem Soc 78:5756–5762

    Article  CAS  Google Scholar 

  17. Calabrese G, Nesnas JJ, Barbu E, Fatouros D, Tsibouklis J (2012) The formation of polyhedral boranes for the boron neutron capture therapy of cancer. Drug Discov Today 17:153–159

    Article  CAS  Google Scholar 

  18. Hawthorne MR (1998) New horizons for therapy based on the boron neutron capture reaction. Mol Med Today 4:174–181

    Article  CAS  Google Scholar 

  19. Kinashi Y, Masunaga S, Takagaki M, Ono K (1997) Mutagenic effects at HPRT locus induced in Chinese hamster ovary cells by thermal neutrons with or without boron compound. Mutat Res 377:211–215

    Article  CAS  Google Scholar 

  20. Nakai H (1985) Increase in mutagenic efficiency of thermal neutrons through boron enrichment in rice seed. Environ Exp Bot 25:385–391

    Article  CAS  Google Scholar 

  21. Saito M (1993) Relative biological effectiveness of the boron neutron-capture beam for the inactivation of biological macromolecules, from annual reports of the Research Reactor Institute. Kyoto Univ 26:59–68

    CAS  Google Scholar 

  22. Lamarsh JR (2002) Introduction to nuclear reactor theory. Addison-Wesley Pub. Co., Reading

    Google Scholar 

  23. Crofoot TA (1989) The determination of oxygen isotopic concentrations by neutron activation analysis and application to the determination of oxygen functional groups in coal by isotopic exchange. Ph.D. Thesis, Department of Chemistry, University of California Irvine

  24. Hopewell JW, Morris GM, Schwint A, Coderre JA (2011) The radiobiological principles of boron neutron capture therapy: a critical review. Appl Radiat Isot 69:1756–1759

    Article  CAS  Google Scholar 

  25. Olszanski A, Klassen NV, Ross CK, Shortt KR (2002) The IRS Fricke dosimetry system. Ionizing Radiation Standards Institute for National Measurement Standards National Research Council Ottawa, Ontario, K1A 0R6

  26. Mezyk SP, Mincher BJ, Ekberg C, Skarnemark G (2012) Alpha and gamma radiolysis of nuclear solvent extraction ligands used for An(III) and Ln(III) separations. J Radioanal Nucl Chem 296:711–715

    Article  Google Scholar 

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Acknowledgments

This project was funded by U.S. Department of Energy through the Nuclear Energy University Program (NEUP) project no. DE-AC07-05ID14517.

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Authors and Affiliations

  1. Department of Chemical Engineering and Materials Science, University of California Irvine, 916 Engineering Tower, Irvine, CA, 92697-2575, USA

    J. Pearson, O. Jan, A. Wariner & M. Nilsson

  2. Department of Chemistry, University of California Irvine, 1102 Natural Sciences 2, Irvine, CA, 92697-2025, USA

    G. E. Miller

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  1. J. Pearson
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  2. O. Jan
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  3. A. Wariner
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  4. G. E. Miller
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  5. M. Nilsson
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Correspondence to M. Nilsson.

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Pearson, J., Jan, O., Wariner, A. et al. Development of a method for high LET irradiation of liquid systems. J Radioanal Nucl Chem 298, 1401–1409 (2013). https://doi.org/10.1007/s10967-013-2549-0

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  • DOI: https://doi.org/10.1007/s10967-013-2549-0

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