Skip to main content
Log in

Facile capture of conjugated polymer nanodots in silica nanoparticles to facilitate surface modification

  • Original Paper
  • Published:
Journal of Materials Science Aims and scope Submit manuscript

Abstract

Conjugated polymer nanodots are shown to have great potential as probe for fluorescence-based biosensing and bioimaging applications. Yet the need to functionalize these polymer nanodots is hindering their uses in many applications. Here, we report the preparation and encapsulation of fluorescent polymer nanodots inside silica nanoparticles. The facile, template-assisted method has little effect on the fluorescent properties of polymer nanodots. The resulting nanodot-embedded silica nanoparticles can be easily functionalized for downstream applications.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1
Fig. 2
Fig. 3
Fig. 4
Fig. 5
Fig. 6
Fig. 7

Similar content being viewed by others

References

  1. Wu C, Bull B, Szymanski C, Christensen K, McNeill J (2008) Multicolor conjugated polymer dots for biological fluorescence imaging. ACS Nano 2:2415–2423

    Article  Google Scholar 

  2. Wu C, Szymanski C, McNeill J (2006) Preparation and encapsulation of conjugated polymer nanoparticles. Langmuir 22:2956–2960

    Article  Google Scholar 

  3. Pecher J, Mecking S (2010) Nanoparticles of conjugated polymers. Chem Rev 110:6260–6279

    Article  Google Scholar 

  4. Tuncel D, Demir HV (2010) Conjugated polymer nanoparticles. Nanoscale 2:484–494

    Article  Google Scholar 

  5. Li K, Liu B (2012) Polymer encapsulated conjugated polymer nanoparticles for fluorescence bioimaging. J Mater Chem 22:1257–1264

    Article  Google Scholar 

  6. Tan H, Zhang Y, Wang M, Zhang Z, Zhang X, Yong AM, Wong SY, Chang AY, Chen Z-K, Li X, Choolani M, Wang J (2012) Silica-shell cross-linked micelles encapsulating fluorescent conjugated polymers for targeted cellular imaging. Biomaterials 33:237–246

    Article  Google Scholar 

  7. Lee CS, Chang HH, Jung J, Lee NA, Song NW, Chung BH (2012) A novel fluorescent nanoparticle composed of fluorene copolymer core and silica shell with enhanced photostability. Colloids Surf B Biointerfaces 91:219–225

    Article  Google Scholar 

  8. Grey JK, Kim DY, Norris BC, Miller WL, Barbara PF (2006) Size-dependent spectroscopic properties of conjugated polymer nanoparticles. J Phys Chem B 110:25568–25572

    Article  Google Scholar 

  9. Kurokawa N, Yoshikawa H, Hirota N, Hyodo K, Masuhara H (2004) Size dependent spectroscopic properties and thermochromic behavior in poly(substituted thiophene) nanoparticles. ChemPhysChem 5:1609–1615

    Article  Google Scholar 

  10. Wu C, Szymanski C, Cain Z, McNeill J (2007) Conjugated Polymer Dots for Multiphoton Fluorescence Imaging. J Am Chem Soc 129:12904–12905

    Article  Google Scholar 

  11. Yu J, Wu C, Sahu SP, Fernando LP, Szymanski C, McNeill J (2009) Nanoscale 3D tracking with conjugated polymer nanoparticles. J Am Chem Soc 131:18410–18414

    Article  Google Scholar 

  12. Szymanski C, Wu C, Hooper J, Salazar MA, Perdomo A, Dukes A, McNeill J (2005) Single molecule nanoparticles of the conjugated polymer Meh–PPV, preparation and characterization by near-field scanning optical microscopy. J Phys Chem B 109:8543–8546

    Article  Google Scholar 

  13. Green M, Howes P, Berry C, Argyros O, Thanou M (2009) Simple conjugated polymer nanoparticles as biological labels. Proc R Soc A 465:2751–2759

    Article  Google Scholar 

  14. Feng X, Lv F, Liu L, Tang H, Xing C, Yang Q, Wang S (2010) Conjugated polymer nanoparticles for drug delivery and imaging. ACS Appl. Mater Interfaces 2:2429–2435

    Article  Google Scholar 

  15. Chong H, Nie C, Zhu C, Yang Q, Liu L, Lv F, Wang S (2012) Conjugated polymer nanoparticles for light-activated anticancer and antibacterial activity with imaging capability. Langmuir 28:2091–2098

    Article  Google Scholar 

  16. Wu C, Bull B, Christensen K, McNeill J (2009) Ratiometric single-nanoparticle oxygen sensors for biological imaging. Angew Chem Int Ed 48:2741–2745

    Article  Google Scholar 

  17. Childress ES, Roberts CA, Sherwood DY, Le Guyader CLM, Harbron EJ (2012) Ratiometric fluorescence detection of mercury ions in water by conjugated polymer nanoparticles. Anal Chem 84:1235–1239

    Article  Google Scholar 

  18. Chan Y, Gallina ME, Zhang X, Wu IC, Jin Y, Sun W, Chiu DT (2012) Reversible photoswitching of spiropyran-conjugated semiconducting polymer dots. Anal Chem 84:9431–9438

    Google Scholar 

  19. Kobler J, Moller K, Bein T (2008) Colloidal suspensions of functionalized mesoporous silica nanoparticles. ACS Nano 4:791–799

    Article  Google Scholar 

  20. Sreejith S, Ma X, Zhao Y (2012) Graphene oxide wrapping on squaraine-loaded mesoporous silica nanoparticles for bioimaging. J Am Chem Soc 134:17346–17349

    Article  Google Scholar 

  21. Han L, Wei H, Tu B, Zhao D (2011) A facile one-pot synthesis of uniform core–shell silver nanoparticle@mesoporous silica nanospheres. Chem Commun 47:8536–8538

    Article  Google Scholar 

Download references

Acknowledgements

This work was partially supported by the National Science Foundation (CBET-1065633).

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Peng Zhang.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Joshi, P.B., Zhang, P. Facile capture of conjugated polymer nanodots in silica nanoparticles to facilitate surface modification. J Mater Sci 50, 3597–3603 (2015). https://doi.org/10.1007/s10853-015-8920-5

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s10853-015-8920-5

Keywords

Navigation