Abstract
Despite prevalence rates as high as 9.4%, few studies have examined the applicability of cognitive-behavioral therapy for treatment of anxiety disorders in very young children (i.e., below the age of 7 years). The present study examined the preliminary efficacy of a parent-led exposure therapy protocol (PLET) designed for young children with anxiety disorders. Twenty-two youth aged 4–7 years and their parents participated in this pilot randomized control trial. Families of youth with significant anxiety concerns were randomized to either PLET (n = 12), a 10 session/5-week family-based exposure therapy program designed to target anxiety in young children, or treatment as usual (TAU; n = 10). Children in the PLET condition demonstrated a greater reduction in anxiety symptoms compared to TAU (d = 3.18), with 90.91% of PLET participants (active condition) being classified as treatment responders at post-treatment as opposed to 0 in the TAU condition. Gains were maintained at 1 month-follow-up. Although pilot in nature, these data suggest in a preliminary fashion that a parent led exposure therapy protocol that is adapted appropriately for developmental age and incorporates an active coaching component for parents may be efficacious for the treatment of young children with anxiety disorders. This clinical trial was registered through clinicaltrials.gov under the following identifier: NCT02051192.
Similar content being viewed by others
References
Bandura, A. (1969). Principles of behavior modification. New York, NY: Holt, Rinehart, & Winston.
Beesdo, K., Knappe, S., & Pine, D. S. (2009). Anxiety and anxiety disorders in children and adolescents: developmental issues and implications for DSM-V. Psychiatric Clinics of North America, 32, 483–524. doi:10.1016/j.psc.2009.06.002.
Bouton, M. (2004). Context and behavioral processes in extinction. Learning and Memory, 11, 485–494. doi:10.1101/lm.78804.
Bufferd, S. J., Dougherty, L. R., Carlson, G. A., Rose, S., & Klein, D. N. (2012). Psychiatric disorders in preschoolers: Continuity from ages 3 to 6. The American Journal of Psychiatry, 169, 1157–1164. doi:10.1176/appi.ajp.2012.12020268.
Cartwright-Hatton, S., McNally, D., Field, A. P., Rust, S., Laskey, B., & Dixon, C., et al. (2011). A new parenting-based group intervention for young anxious children: Results of a randomized controlled trial. Journal of the American Academy of Child and Adolescent Psychiatry, 50, 242–251. doi:10.1016/j.jaac.2010.12.015.
Chu, B. C., Skriner, L. C., & Zandberg, L. J. (2013). Shape of change in cognitive behavioral therapy for youth anxiety: Symptom trajectory and predictors of change. Journal of Consulting and Clinical Psychology, 81, 573–587. doi:10.1037/a0033390.
Comer, J. S., Puliafico, A. C., Aschenbrand, S. G., McKnight, K., Robin, J. A., Goldfine, M. E., & Albano, M. (2012). A pilot feasibility evaluation of the CALM program for anxiety disorders in early childhood. Journal of Anxiety Disorders, 26(1), 40–49. doi:10.1016/j.janxdis.2011.08.011.
Costello, E. J., Egger, H. L., Copeland, W., Erkanli, A., & Angold, A. (2011). The developmental epidemiology of anxiety disorders: Phenomenology, prevalence, and comorbidity. In W. K. Silverman, & A. P. Field (Eds.), Anxiety disorders in children and adolescents: Research, assessment and intervention (pp. 56–75). New York, NY: Cambridge University Press.
Davis, III, T. E., May, A. C., & Whiting, S. E. (2011). Evidence-based treatment of anxiety and phobia in children and adolescents: current status and effects on the emotional response. Clinical Psychology Review, 31, 592–602. doi:10.1016/j.cpr.2011.01.001.
Davis, III, T. E., & Ollendick, T. H. (2005). Empirically supported treatments for specific phobia in children: Do efficacious treatments address the components of a phobic response? Clinical Psychology: Science and Practice, 12, 144–160. doi:10.1093/clipsy.bpi018.
Egger, H. L., & Angold A. (2006). Common emotional and behavioral disorders in preschool children: presentation, nosology, and epidemiology. Journal of Child Psychology and Psychiatry, 47, 313–337
Ezpeleta, L., Keeler, G., Alaatin, E., Costello, E. J., & Angold, A. (2001). Epidemiology of psychiatric disability in childhood and adolescence. Journal of Child Psychology and Psychiatry, 42, 901–914. doi:10.1111/1469-7610.00786.
Flavell, J. H., Miller, P. H., & Miller, S. A. (2001). Cognitive development (4th ed.). New York, NY: Prentice Hall.
Freeman, J. B., Garcia, A. M., Coyne, L., Ale, C., Przeworski, A., Himle, M., Compton, S., & Leonard, H. L. (2008). Early childhood OCD: Preliminary findings from a family-based cognitive-behavioral approach. Journal of the American Academy of Child and Adolescent Psychiatry, 47, 593–602. doi:10.1097/CHI.0b013e31816765f9.
Freeman, J. B., Sapyta, J., Garcia, A., Compton, S., Khanna, M., & Flessner, C., et al. (2014). Family-based treatment of early childhood obsessive-compulsive disorder. The pediatric obsessive-compulsive disorder treatment study for young children (POTS Jr)-A randomized clinical trial. JAMA Psychiatry, 71, 689–698. doi:10.1001/jamapsychiatry.2014.170.
Ginsburg, G. S., Keeton, C. P., Drazdowski, T. K., & Riddle, M. A. (2011). The utility of clinicians ratings of anxiety using the pediatric anxiety rating scale (PARS). Child and Youth Care Forum, 40, 93–105. doi:10.1007/s10566-010-9125-3.
Guy, W. (1976). Clinical global impressions. In: ECDEU assessment manual for psychopharmacology, revised. (pp. 218–222). Rockville, MD: U.S. Department of Health, Education, and Welfare.
Hirshfeld-Becker, D. R., & Biederman, J. (2002). Rationale and principles for early intervention with young children at risk for anxiety disorders. Clinical Child and Family Psychology Review, 5, 161–172. doi:10.1023/A:1019687531040.
Hirshfeld-Becker, D. R., Masek, B., Henin, A., Blakely, L. R., Pollock-Wurman, R. A., & McQuade, J., et al. (2010). Cognitive behavioral therapy for 4- to 7-year-old children with anxiety disorders: a randomized clinical trial. Journal of Consulting and Clinical Psychology, 78, 498–510. doi:10.1037/a0019055.
Horwitz, S. M., Hoagwood, K., Stiffman, A. R., Summerfeld, T., Weisz, J. R., & Costello, J., et al. (2001). Reliability of the services assessment for children and adolescents. Psychiatric Services, 52, 1088–1094. doi:10.1176/appi.ps.52.8.1088.
Johnco, C. J., Salloum, A., Lewin, A. B., & Storch, E. A. (2015). Refining clinical judgment of treatment response and symptom remission identification in childhood anxiety using a signal detection analysis on the pediatric anxiety rating scale. Journal of Child and Adolescent Psychopharmacology, 25, 674–683. doi:10.1089/cap.2015.0102.
Karevold, E., Roysamb, E., Ystrom, E., & Mathiesen, K. S. (2009). Predictors and pathways from infancy to symptoms of anxiety and depression in early adolescence. Developmental Psychology, 45, 1051–1060. doi:10.1037/a0016123.
Labouliere, C. D., Arnold, E. A., Storch, E. A., & Lewin, A. B. (2014). Family-based cognitive-behavioral treatment for a preschooler with obsessive compulsive disorder. Clinical Case Studies, 13, 37–51. doi:10.1177/1534650113504985.
Lebowitz, E. R., Woolston, J., Bar-Haim, Y., Calvocoressi, L., Dauser, C., & Warnick, E., et al. (2013). Family accommodation in pediatric anxiety disorders. Depression and Anxiety, 30, 47–54. doi:10.1002/da.21998.
Leitenberg, H., & Callahan, E. J. (1973). Reinforced practice and reduction of different kinds of fears in adults and children. Behaviour Research and Therapy, 11, 19–30. doi:10.1016/0005-7967(73)90065-X.
Lewin, A. B., McGuire, J. F., Murphy, T. K., & Storch, E. A. (2014). Editorial perspective: The importance of considering parent’s preferences when planning treatment for their children - The case of childhood obsessive-compulsive disorder. Journal of Child Psychology and Psychiatry, 55, 1314–1316. doi:10.1111/jcpp.12344.
Lewin, A. B., Park, J. M., Jones, A. M., Crawford, E. A., DeNadai, A. S., & Menzel, J., et al. (2014). Family-based exposure and response prevention therapy for preschool-aged children with obsessive-compulsive disorder: A pilot randomized controlled trial. Behaviour Research and Therapy, 56, 30–38. doi:10.1016/j.brat.2014.02.001.
May, A. C., Rudy, B. M., Davis, T. E., & Matson, J. L. (2012). Evidence-based behavioral treatment of dog phobia with young children: Two case examples. Behavior Modification, 37, 143–160. doi:10.1177/0145445512458524.
Minde, K., Roy, J., Bezonsky, R., & Hashemi, A. (2010). The effectiveness of CBT in 3-7 year old anxious children: Preliminary data. Journal of the Canadian Academy of Child and Adolescent Psychiatry, 19, 109–115.
Monga, S., Rosenbloom, B. N., Tanha, A., Owens, M., & Young, A. (2015). Comparison of child-parent and parent-only cognitive-behavioral therapy programs for anxious children aged 5 to 7 years: Short- and long-term outcomes. Journal of the American Academy of Child and Adolescent Psychiatry, 54, 138–146. doi:10.1016/j.jaac.2014.10.008.
Monga, S., Young, A., & Owens, M. (2009). Evaluating a cognitive behavioral therapy group program for anxious five to seven year old children: A pilot study. Depression and Anxiety, 26, 243–250. doi:10.1002/da.20551.
Myers, K., & Davis, M. (2002). Behavioral and neural analysis of extinction. Neuron, 36, 567–584. doi:10.1101/lm.119806.
National Institute of Mental Health. (1985). Clinical global impressions. Psychopharmacology Bulletin, 21, 839–843.
Ollendick, T. H., Halldorsdottir, T., Fraire, M. G., Austin, K. E., Noguchi, R. J., & Lewis, K. M., et al. (2015). Specific phobias in youth: A randomized controlled trial comparing one-session treatment to a parent-augmented one-session treatment. Behavior Therapy, 46, 141–155. doi:10.1016/j.beth.2014.09.004.
Rapee, R. M., Kennedy, S. J., Ingram, M., Edwards, S. L., & Sweeney, L. (2010). Altering the trajectory of anxiety in at-risk young children. American Journal of Psychiatry, 167, 1518–1525. doi:10.1176/appi.ajp.2010.09111619.
RUPP (Research Units of Pediatric Psychopharmacology) Group. (2002). The pediatric anxiety rating scale: Development and psychometric properties. Journal of the American Academy of Child and Adolescent Psychiatry, 41, 1061–1069.
Settipani, C. A., O’Neil, K. A., Podell, J. L., Beidas, R. S., & Kendall, P. C. (2013). Youth anxiety and parent factors over time: Directionality of change among youth treated for anxiety. Journal of Clinical Child & Adolescent Psychology, 42(1), 9–21. doi:10.1080/15374416.2012.719459.
Silverman, W. K., & Albano, A. M. (1996). The anxiety disorders interview schedule for DSM-IV-child and parent versions. San Antonio, TX: Graywinds Publications, A division of the Psychological Corporation.
Storch, E. A., Zavrou, S., Collier, A. B., Ung, D., Arnold, E. B., Mutch, P. J., Lewin, A. B., & Murphy, T. K. (2015). Preliminary study of family accommodation in youth with autism spectrum disorders and anxiety: Incidence, clinical correlates, and behavioral treatment response. Journal of Anxiety Disorders, 10.1016/j.janxdis.2015.06.007
Towe-Goodman, N. R., Franz, L., Copeland, W., Angold, A., & Egger, H. (2014). Perceived family impact of preschool anxiety disorders. Journal of the American Academy of Child and Adolescent Psychiatry, 53, 437–446. doi:10.1016/j.jaac.2013.12.017.
van der Sluis, C. M., van der Bruggen, C. O., Brechman-Toussaint, M. L., Thissen, M. A. P., & Bogels, S. M. (2012). Parent-directed cognitive behavioral therapy for young anxious children: A pilot study. Behavior Therapy, 43, 583–592. doi:10.1016/j.beth.2011.10.002.
Walkup, J. T., Albano, A. M., & Piacentini, J., et al. (2008). Cognitive behavioral therapy, sertraline, or a combination in childhood anxiety. New England Journal of Medicine, 359, 2753–2766. doi:10.1056/NEJMoa0804633.
Acknowledgements
E.A.S. receives research support from the National Institutes of Health, International OCD foundation, and All Children’s Hospital Research Foundation. E.A.S. also receives book royalties from the American Psychological Association, Wiley, Elsevier, and Springer. A.B.L. receives research support from the Centers for Disease Control and Prevention, Tourette Association of America, International OCD Foundation, and All Children’s Hospital. A.B.L. consults for Brackett LLC.
Author information
Authors and Affiliations
Corresponding author
Ethics declarations
Conflict of Interest
The authors declare that they have no competing interests.
Ethical Approval
All applicable international, national, and/or institutional guidelines for the use of human participants were followed. This article does not contain any studies with animals performed by any of the authors.
Informed Consent
Informed consent was obtained from all individual participants’ parents (legal guardians) included in the study. No identifying information about participants is available in the article.
Rights and permissions
About this article
Cite this article
Rudy, B.M., Zavrou, S., Johnco, C. et al. Parent-Led Exposure Therapy: A Pilot Study of a Brief Behavioral Treatment for Anxiety in Young Children. J Child Fam Stud 26, 2475–2484 (2017). https://doi.org/10.1007/s10826-017-0772-y
Published:
Issue Date:
DOI: https://doi.org/10.1007/s10826-017-0772-y