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Telephone Based Cognitive Behavioral Therapy Targeting Major Depression Among Urban Dwelling, Low Income People Living with HIV/AIDS: Results of a Randomized Controlled Trial

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Abstract

This pilot randomized controlled trial evaluated a previously developed manualized telephone based cognitive behavioral therapy (T-CBT) intervention compared to face-to-face (f2f) therapy among low-income, urban dwelling HIV infected depressed individuals. The primary outcome was the reduction of depressive symptoms as measured by the Hamliton rating scale for depression scale. The secondary outcome was adherence to HAART as measured by random telephone based pill counts. Outcome measures were collected by trained research assistants masked to treatment allocation. Analysis was based on intention-to-treat. Thirty-four participants met eligibility criteria and were randomly assigned to receive T-CBT (n = 16) or f2f (n = 18). There was no statistically significant difference in depression treatment outcomes comparing f2f to T-CBT. Within group evaluation demonstrated that both the T-CBT and the f2f psychotherapy groups resulted in significant reductions in depressive symptoms. Those who received the T-CBT were significantly more likely to maintain their adherence to antiretroviral medication compared to the f2f treatment. None of the participants discontinued treatment due to adverse events. T-CBT can be delivered to low-income, urban dwelling HIV infected depressed individuals resulting in significant reductions in depression symptoms and improved adherence to antiretroviral medication. Trial Registry: Clinical Trial.gov identifier: NCT01055158.

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Acknowledgments

This project was supported by the National Institute of Mental Health (R34- MH80630)

Disclaimer

The views expressed in this paper are those of the authors. No official endorsement by the National Institutes of Health is intended or should be inferred.

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Authors and Affiliations

  1. Department of Psychiatry, Division of Services Research, University of Maryland School of Medicine, 737 West Lombard St., Room 516, Baltimore, MD, 21212, USA

    Seth Himelhoch, Deborah Medoff, Charles Robinson & Wendy Potts

  2. Mid-America Christian University College of Adult and Graduate Studies, Oklahoma City, OK, USA

    Jennifer Maxfield

  3. Baltimore, MD, USA

    Sarah Dihmes

  4. New York State Psychiatric Institute, New York, NY, USA

    Lisa Dixon

  5. Department of Preventive Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA

    David C. Mohr

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  1. Seth Himelhoch
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Correspondence to Seth Himelhoch.

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Himelhoch, S., Medoff, D., Maxfield, J. et al. Telephone Based Cognitive Behavioral Therapy Targeting Major Depression Among Urban Dwelling, Low Income People Living with HIV/AIDS: Results of a Randomized Controlled Trial. AIDS Behav 17, 2756–2764 (2013). https://doi.org/10.1007/s10461-013-0465-5

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  • DOI: https://doi.org/10.1007/s10461-013-0465-5

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