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Comparing Diffusion Approximation with Radiation Transfer Analysis for Light Transport in Tissues

  • ENVIRONMENTAL, BIOLOGICAL, AND SPACE OPTICS
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Abstract

The diffusion model that is an approximation of the equation of radiation transfer is typically used to describe photon migration in scattering-dominant media. In general biological tissue is highly scattering and very weakly absorbing against near-infrared light, yet it is heterogeneous and may contain relatively highly absorbing or low-scattering regions. Here applicability of the diffusion approximation over the radiative transfer theory for describing ultrafast laser transport in biological tissues is numerically studied and investigated over different kinds of tissue conditions and geometries. Tissues having tumors of different sizes, locations and nature as well as dual-tumor and low-scattering conditions are considered. Radiation transfer analysis is taken as a comparison objective and it is initially proved to be accurate in benchmark comparisons with Monte Carlo simulation. The results predict systematically about the compatible conditions where and when we can use the diffusion approximation and the conditions in which the diffusion approximation may provide misleading results.

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References

  1. Y. Yamada: Ann. Rev. Fluid Mech. Heat Transf., ed. C. L. Tien, 6 (1995) 1.

  2. R. R. Alfano, S. G. Demos and S. K. Gayen: Ann. New York Acad. Sci. 820 (1997) 248.

    Google Scholar 

  3. A. G. Yodh and B. Chance: Phys. Today 48 (1995) 34.

    Google Scholar 

  4. S. R. Arridge and J. C. Hebden: Int. J. Imaging Syst. & Technol. 11 (2000) 2.

    Google Scholar 

  5. F. Gao, H. J. Zhao and Y. Yamada: Appl. Opt. 41 (2002) 778.

    PubMed  Google Scholar 

  6. Y. Nomura, O. Hazeki and M. Tamura: Phys. Med. & Biol. 42 (1997) 1009.

    Google Scholar 

  7. C. Sato, M. Nemoto and M. Tamura: Jpn. J. Physiol. 52 (2002) 301.

    Article  PubMed  Google Scholar 

  8. K. Ishii, T. Iwai and T. Asakura: J. Opt. Soc. Am. A 14 (1997) 179.

    Google Scholar 

  9. S. Kumar, K. Mitra and Y. Yamada: Appl. Opt. 35 (1996) 3372.

    Google Scholar 

  10. Z. Guo, J. Aber, B. Garetz and S. Kumar: J. Quant. Spectrosc. & Radiat. Transfer 73 (2002) 159.

    Google Scholar 

  11. Z. Guo and S. Kumar: Appl. Opt. 40 (2001) 3156.

    PubMed  Google Scholar 

  12. Z. Guo and S. Kumar: J. Thermophys. Heat Transfer 16 (2002) 289.

    Google Scholar 

  13. Z. Guo and S. Kumar: Numer. Heat Transfer B 39 (2001) 371.

    Article  Google Scholar 

  14. A. Ishimaru: Appl. Opt. 28 (1989) 2210.

    Google Scholar 

  15. Y. Yamada and Y. Hasegawa: Proc. SPIE, 1888 (1993) 167.

  16. Y. Takahashi and Y. Yamada: Proc. SPIE, 2626 (1995) 103.

  17. M. Patterson, B. Chance and B. Wilson: Appl. Opt. 28 (1989) 2331.

    Google Scholar 

  18. Y. Ueda and K. Ohta: Appl. Opt. 40 (2001) 6349.

    Google Scholar 

  19. K. Furutsu and Y. Yamada: Phys. Rev. E 50 (1994) 3634.

    Article  Google Scholar 

  20. M. Bassani, F. Martelli, G. Zaccanti and D. Contini: Opt. Lett. 22 (1997) 853.

    Google Scholar 

  21. T. Durduran, A. G. Yodh, B. Chance and D. A. Boas: J. Opt. Soc. Am. A 14 (1997) 3358.

    Google Scholar 

  22. K. Rinzema, L. H. P. Murrer and W. M. Star: J. Opt. Soc. Am. A 15 (1998) 2078.

    Google Scholar 

  23. R. Aronson and N. Corngold: J. Opt. Soc. Am. A 16 (1999) 1066.

    Google Scholar 

  24. W. Cai, M. Xu, M. Lax and R. R. Alfano: Opt. Lett. 27 (2002) 731.

    Google Scholar 

  25. K. M. Yoo, F. Liu and R. R. Alfano: Phys. Rev. Lett. 64 (1990) 2647.

    Article  PubMed  Google Scholar 

  26. Z. Guo and S. Kumar: Appl. Opt. 39 (2000) 4411.

    Google Scholar 

  27. W. F. Cheong and S. A. Prahl: IEEE J. Quant. Electr. 26 (1990) 2166.

    Article  Google Scholar 

  28. Z. Guo, S. Kumar and K. C. San: J. Thermophys. Heat Transfer. 14 (2000) 504.

    Google Scholar 

  29. M. Firbank, S. R. Arridge, M. Schweiger and D. T. Deply: Phys. Med. & Biol. 41 (1996) 767.

    Google Scholar 

  30. E. Okada, M. Firbank, M. Schweiger, S. R. Arridge, M. Cope and D. T. Deply: Appl. Opt. 36 (1997) 21.

    Article  Google Scholar 

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Correspondence to Zhixiong Guo.

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Guo, Z., Wan, S.K., Kim, K. et al. Comparing Diffusion Approximation with Radiation Transfer Analysis for Light Transport in Tissues. OPT REV 10, 415–421 (2003). https://doi.org/10.1007/s10043-003-0415-y

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  • DOI: https://doi.org/10.1007/s10043-003-0415-y

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