Abstract
The centromedian nucleus (CM) of the thalamus is an important site with anatomical connections to different cortical and subcortical motor areas; however, its role in tremor disorders is not clear, although deep brain stimulation (DBS) of the CM has been described to be effective in the treatment of parkinsonian tremor. We report a case of a patient with medication-refractory essential tremor (ET) who had excellent tremor suppression with DBS of the CM. The CM and the nearby region should be explored as a potential target for the treatment of ET and other forms of tremor.
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Thomas Wichmann: The writing of this article was supported by a grant from the NIH/ORIP to the Yerkes Center (P51-OD011132). Mahlon DeLong: received support from APDA for writing this article.
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This is an interesting case report describing the complexity of surgical treatments of movement disorders. It is well written and the discussion of possible mechanisms of CM having a role in ET is good.
Ulrike Sandvik
Stockholm, Sweden
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Sharma, V.D., Mewes, K., Wichmann, T. et al. Deep brain stimulation of the centromedian thalamic nucleus for essential tremor: a case report. Acta Neurochir 159, 789–793 (2017). https://doi.org/10.1007/s00701-017-3143-y
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DOI: https://doi.org/10.1007/s00701-017-3143-y