Zusammenfassung
Die transretinale Tumorbiopsie gewinnt einen zunehmend höheren Stellenwert in der Diagnostik intraokularer Raumforderungen. Moderne Techniken der transretinalen Biopsie können die histopathologische Diagnose vor Beginn der Therapie sichern. Zusätzlich können durch die molekulargenetische Analyse maligner Melanome der Uvea Hochrisikotumoren mit hohem Metastasierungsrisiko identifiziert werden. Die unterschiedlichen Biopsietechniken, Indikationen und Anwendungsgebiete werden deshalb im Folgenden dargestellt.
Abstract
Transretinal biopsy of intraocular tumors plays a decisive role as a diagnostic tool in ocular oncology. A biopsy is indicated to confirm a clinical diagnosis before treatment and allows identification of high risk melanomas of the uvea with a high potential of metastasis by molecular genetic evaluation of the specimen. This review will focus on the various biopsy techniques and indications for this method.
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Interessenkonflikt
E. Biewald, K.A. Metz und N. Bornfeld geben an, dass kein Interessenkonflikt besteht. Dieser Beitrag beinhaltet keine Studien an Menschen oder Tieren.
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Biewald, E., Metz, K. & Bornfeld, N. Stellenwert der transretinalen Tumorbiopsie als diagnostisches und prädiktives Instrument. Ophthalmologe 110, 882–884 (2013). https://doi.org/10.1007/s00347-013-2905-z
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DOI: https://doi.org/10.1007/s00347-013-2905-z
Schlüsselwörter
- Genetische Aufarbeitung
- Monosomie 3
- Aderhautmelanom
- Intraokulare Raumforderungen
- Histopathologische Diagnose