Summary.
Rat dams were exposed to 15% ethanol containing water ad libitum for 24 h at the 3rd day of gestation. Adult progenies’ immune cells (peritoneal, blood and thymic lymphocytes, monocyte-macrophage-granulocyte group and mast cells) were studied by flow cytometry for binding of FITC-labelled insulin (compared to the appropriate cells of untreated animals). All of the cell types studied bound significantly less insulin, except mast cells. The results call attention to the life-long effect of occasional alcohol consumption in early pregnancy manifested in the immune system.
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Received 27 June 2005; returned for revision 23 August 2005; accepted by I. Ahnfelt-Rønne 29 August 2005
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Pállinger, É., Csaba, G. Effect of a single early-gestational alcohol consumption on the insulin binding by immune cells of adult rats. Inflamm. res. 54, 483–484 (2005). https://doi.org/10.1007/s00011-005-1383-4
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DOI: https://doi.org/10.1007/s00011-005-1383-4