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Human but not ovine isolates ofBordetella parapertussis are highly clonal as determined by PCR-based RAPD fingerpringting

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Summary

The DNA fingerprints of 170 human isolates and ten ovine isolates ofBordetella parapertussis were examined by arbitrarily-primed PCR/RAPD with 29 primers. Based on this technique, all the human isolates appear highly genetically homogenous. The ovine isolates could be distinguished from human isolates and they showed diversity among themselves. Therefore, human isolates ofB. parapertussis are a highly clonal group adapted to infect humans and they are distinct from polymorphic ovine isolates.

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Author notes

  1. G. Martínez de Tejada Ph.D.

    Present address: Departmento de Microbiologia, Universidad de Navarro, Aptdo. 273, E-31080, Pamplona, Spain

Authors and Affiliations

  1. Dept. of Microbiology and Immulogy, UCLA School of Medicine, 10833 Le Conte Ave., 90095-174, Los Angeles, CA, USA

    M. H. Yuk Ph.D., U. Heininger M.D., G. Martínez de Tejada Ph.D. & J. F. Miller M.D.

  2. Universitätsklinik für Kinder und Jugendliche, Erlangeny, Germany

    U. Heininger M.D.

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  1. M. H. Yuk Ph.D.
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  3. G. Martínez de Tejada Ph.D.
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  4. J. F. Miller M.D.
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Yuk, M.H., Heininger, U., Martínez de Tejada, G. et al. Human but not ovine isolates ofBordetella parapertussis are highly clonal as determined by PCR-based RAPD fingerpringting. Infection 26, 270–273 (1998). https://doi.org/10.1007/BF02962245

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  • DOI: https://doi.org/10.1007/BF02962245

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