Skip to main content
Log in

Primary care anticoagulant management using near patient testing

  • Original Paper
  • Published:
Irish Journal of Medical Science Aims and scope Submit manuscript

Abstract

Background Indications for anticoagulant treatment are increasing and new approaches to anticoagulant services require a shift from hospital to primary care.

Aim To pragmatically test the validity and effectiveness of primary care anticoagulant management using near patient testing.

Methods Twelve CoaguCheck monitors were supplied to 16 rural practices that had previously provided supervision of anticoagulant therapy. Practices were required to record data for eligible patients from September 1998 to April 1999 and to forward one blood sample per week to the regional hospital laboratory for parallel testing.

Results Nine practices returned data on 122 patients. Indications for anticoagulation included atrial fibrillation (n=56), valve replacement (n=12) and deep venous thrombosis or pulmonary embolus (n=12). Regression of the mean of 185 paired readings against their difference confirmed the validity of the CoaguCheck monitor (r2 = 0.00 [95% CI -0.38 to 0.38]). There were 692 International Normalised Ratio (INR) tests performed representing an average of 5.7 tests per patient. The desired therapeutic range was provided for 609 (88%) of these tests; 294 (48.3%) were within the desired therapeutic range. Results differed significantly between practices.

Conclusions This study confirmed the validity of anticoagulant management using the CoaguCheck monitor in primary care.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  1. Rose PE, Fitzmaurice D. New approaches to the delivery of anticoagulant services.Blood Reviews 1998; 12: 84–90.

    Article  PubMed  CAS  Google Scholar 

  2. Fitzmaurice DA, Hobbs FDR, Murray ET. Evaluation of computerised decision support for oral anticoagulation management based in primary care.BJGP 1996; 46: 533–5.

    CAS  Google Scholar 

  3. Roca RA. Anticoagulant therapy.BJGP 1993; 44: 393.

    Google Scholar 

  4. Fitzmaurice DA, Hobbs FDR, Murray ET. Primary care anticoagulant clinic management using computerised decision support and near patient INR testing: routine data from a practice nurse led-clinic.Family Practice 1998; 15: 144–6.

    Article  PubMed  CAS  Google Scholar 

  5. Macgregor SH, Hamley JG, Dunbar JA, Dodd TRP, Cromarty JA. Evaluation of a primary care anticoagulant clinic managed by a pharmacist.BMJ 1996; 312: 560.

    PubMed  CAS  Google Scholar 

  6. Pell JP, McIver B, Stuart P, Malone DNS, Alcock J. Comparison of anticoagulant control among patients attending general practice and a hospital anticoagulant clinic.BJGP 1993; 43: 152–4.

    CAS  Google Scholar 

  7. Shakespeare J. Anticoagulation in patients with atrial fibrillation.BMJ 1994; 308: 415.

    PubMed  CAS  Google Scholar 

  8. Good J. The monitoring of prothrombin time ratios in general practice.Ir Med J 1991; 84: 126–7.

    PubMed  CAS  Google Scholar 

  9. Pocock SJ. Clinical trials: a practical approach. New York: Wiley, 1983.

    Google Scholar 

  10. NMIC (National Medicines Information Centre). Oral anticoagulants. 1996; 2 (6).

  11. British Society for Haematology. Guidelines on oral anticoagulation: second edition.J Clin Pathol 1990; 43: 177–83.

    Article  Google Scholar 

  12. Hobbs FDR, Fitzmaurice DA. Where should oral anticoagulation monitoring take place?BJGP 1997; 47: 479–80.

    CAS  Google Scholar 

  13. van den Besselaar AMHP. Recommended method for re p o rting therapeutic control of oral anticoagulation therapy.Thrombosis and Haemostasis 1990; 63: 316–7.

    PubMed  Google Scholar 

  14. Bland JM, Altman DG. Statistical methods for assessing agreement between two methods of clinical measurement.The Lancet 1986; i: 307–10.

    Google Scholar 

  15. McLean KF. Anticoagulant therapy.BJGP 1993; 44: 393.

    Google Scholar 

  16. Galloway MJ, Foggin JJ, Dixon S. Introduction of computer assisted control of oral anticoagulation in general practice.J Clin Pathol 1995; 48: 1144–6.

    Article  PubMed  CAS  Google Scholar 

  17. Hasenkam JM, Kimose HH, Knudsen L et al. Self-management of oral anticoagulant therapy after heart valve replacement.Eur J Cardiothoracic Surg 1997; 11: 935–42.

    Article  CAS  Google Scholar 

  18. Cromheecke ME, Levi M, Colly LP et al. Oral anticoagulation self-management and management by a specialist anticoagulation clinic: a randomised, cross-over comparison.The Lancet 2000; 356: 97–102.

    Article  CAS  Google Scholar 

  19. Casey M, Hanley K. A measurement of the efficacy of anticoagulation monitoring in a general practice based setting.Ir Med J 2001; 94: 245–6.

    PubMed  CAS  Google Scholar 

  20. Jennings I, Luddington RJ, Baglin T. Evaluation of the Ciba Corning Biotrack 512 coagulation monitor for the control of oral anticoagulation.J Clin Pathol 1991; 44: 950–3.

    Article  PubMed  CAS  Google Scholar 

  21. Lucas FV, Duncan A, Jay R. A novel whole blood capillary technique for measuring the prothrombin time.Am J Clin Pathol 1987; 88: 442–6.

    PubMed  CAS  Google Scholar 

  22. Anderson DR, Harrison I, Hirsh J. Evaluation of a portable prothrombin time monitor for home use by patients who require long-term oral anticoagulant therapy.Arch Intern Med 1993; 153: 1441–7.

    Article  PubMed  CAS  Google Scholar 

  23. Seamark DA, Backhouse S, Barber P et al. Validation of current practice and a near patient testing method for oral anticoagulant control in general practice. J R Soc Med 1997; 90: 657–60.

    PubMed  CAS  Google Scholar 

  24. Doble N, Baron JH. Anticoagulation control with warfarin by junior hospital doctors.J R Soc Med 1987; 80: 627.

    PubMed  CAS  Google Scholar 

  25. Poller L, Wright D, Rowlands M. Prospective comparative study of computer programs used for management of warfarin.J Clin Pathol 1993; 46: 299–303.

    Article  PubMed  CAS  Google Scholar 

  26. Hobbs R, Delaney BC, Fitzmaurice D et al. A review of near patient testing in primary care.Health Technol Assess 1997; 1 (5).

  27. Fitzmaurice DA, Raftery JP, Bryan S. Policy dilemmas for oral anticoagulation management.Br J Gen Pract 2000; 50: 779–80.

    PubMed  CAS  Google Scholar 

  28. Parry D, Bryan S, Gee K, Murray E, Fitzmaurice D. Patient costs in anticoagulation management: a comparison of primary and secondary care.Br J Gen Pract 2001; 51: 972–6.

    PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Daly, M., Murphy, A., O’Hanlon, C. et al. Primary care anticoagulant management using near patient testing. Ir J Med Sci 172, 30–32 (2003). https://doi.org/10.1007/BF02914783

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF02914783

Keywords

Navigation