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The determination of bone fracture properties by dual-energy X-ray absorptiometry and single-photon absorptiometry: A comparative study

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Summary

Dual-energy X-ray absorptiometry (DEXA) and single-photon absorptiometry (SPA) were used to quantitate the structural strength and local material properties of healing tibial osteotomies in 32 dogs. Dogs were divided into four equal groups, euthanatized at either 2, 4, 8, or 12 weeks, and imaged with DEXA and SPA. Invasive techniques were used to determine (1) the torsional properties of the bone, (2) the local stiffness properties and calcium content within the bone, and (3) new bone formation and porosity by histology. There were no differences between SPA and DEXA in their associations with the torsional properties of bone. SPA and DEXA had strong correlations with the ultimate torque (R2=0.76, 0.51) and the torsional stiffness (R2=0.68, 0.53) of bone. SPA and DEXA of periosteal callus, endosteal callus, and cortical bone had similar associations with indentation stiffness, calcium content, new bone formation, and porosity. SPA of gap tissue had significantly stronger associations with these four parameters than DEXA (P<0.05). Correlation coefficients (R2) with these local material properties ranged as high as 0.82 for SPA with new bone formation in the gap tissue and 0.73 for DEXA with indentation stiffness of periosteal callus.

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Authors and Affiliations

  1. Biomechanics Laboratory, Department of Orthopedics, Mayo Clinic/Mayo Foundation, 55905, Rochester, MN, USA

    Mark D. Markel, Mark A. Wikenheiser, David G. Lewallen & Edmund Y. S. Chao

  2. Department of Diagnostic Radiology, Mayo Clinic/Mayo Foundation, 55905, Rochester, MN, USA

    Richard L. Morin

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  1. Mark D. Markel
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  2. Mark A. Wikenheiser
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  3. Richard L. Morin
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  4. David G. Lewallen
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  5. Edmund Y. S. Chao
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Markel, M.D., Wikenheiser, M.A., Morin, R.L. et al. The determination of bone fracture properties by dual-energy X-ray absorptiometry and single-photon absorptiometry: A comparative study. Calcif Tissue Int 48, 392–399 (1991). https://doi.org/10.1007/BF02556452

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  • DOI: https://doi.org/10.1007/BF02556452

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