Summary
Cytotoxic T-lymphocytes (CTLs) kill abnormal cells. CTLs recognize major histocompatibility complex class I molecules in complex with peptides derived from relevant antigens. The identification of tumor associated antigen peptides enabled the design of anti-tumor and anti-metastatic vaccines in a murine lung carcinoma.
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Eisenbach, L., Mandelboim, O., Bar-Haim, E. et al. Tumor-associated antigen peptides as anti-metastatic vaccines. Lett Pept Sci 5, 323–328 (1998). https://doi.org/10.1007/BF02443479
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DOI: https://doi.org/10.1007/BF02443479