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Optical rotatory dispersion of proline-rich peptides from the venom ofBothrops jararaca

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  • Chimica, Biochimica, Biophysica
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Zusammenfassung

Die optische Rotationsdispersion mehrer prolinreicher Oligopeptide aus dem Gift der SchlangeBothrops jararaca wurde gemessen und mit jener von Oligoprolinen verglichen. Es konnte nur eine qualitative Beziehung zwischen der angedeuteten Strukturrigidität und der biologischen Wirksamkeit der Peptide festgestellt werden.

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Literatur

  1. S. H. Ferreira, Br. J. Pharmac. Chemother.24, 163 (1965).

    Article  CAS  Google Scholar 

  2. Y. S. Bakhle, Nature, Lond.220, 919 (1968).

    Article  CAS  Google Scholar 

  3. S. H. Ferreira, D. C. Bartelt andL. J. Greene, Biochemistry9, 2583 (1970).

    Article  CAS  Google Scholar 

  4. M. A. Ondetti, N. J. Williams, E. F. Sabo, J. Pluscec, E. R. Weaver andO. Kocy, 2nd American Peptide Symposium, Cleveland, Ohio, August, 1970 (in press).

  5. D. W. Cushman andH. S. Cheung, Fedn. Proc.28, Abstr. 3019 (1969).

    Google Scholar 

  6. H. Okabayashi, T. Isemura andS. Sakakibara, Biopolymers6, 307 (1968).

    Article  Google Scholar 

  7. J. P. Carver andE. R. Blout inTreatise on Collagen (G. Ramachandran; Academic press, New York, 1967), vol. 1, p. 441.

    Google Scholar 

  8. T. Isemura, H. Okabayashi andS. Sakakibara, Biopolymers6, 317 (1968).

    Article  Google Scholar 

  9. M. Bodanszky, M. A. Ondetti, J. T. Sheehan andS. Lande, J. Am. chem. Soc.85, 991 (1963).

    Article  CAS  Google Scholar 

  10. A. Bodanszky, M. Bodanszky, E. J. Jorpes, V. Mutt andM. A. Ondetti, Experientia26, 948 (1970).

    Article  CAS  Google Scholar 

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This study was supported by a U.S. Public Health Service Grant No. 1RO1-AM-12473. ProfessorRosalia B. Frydman, Department of Biochemistry, University of Buenos Aires, Argentina, during her visit at Case Western Reserve University, participated in the experiments here reported.

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Bodanszky, A., Ondetti, M.A., Ralofsky, C.A. et al. Optical rotatory dispersion of proline-rich peptides from the venom ofBothrops jararaca. Experientia 27, 1269–1270 (1971). https://doi.org/10.1007/BF02136679

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  • DOI: https://doi.org/10.1007/BF02136679

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