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Amnesic effects of intravenous diazepam and lorazepam

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Summary

The amnesic effects of 2 benzodiazepine drugs, diazepam (Valium) and lorazepam (Ativan), have been investigated. Some of the effects were similar to those of certain clinical amnesic syndromes. The effects were more extensive than previous work has indicated.

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Author notes

  1. Vivien Lewis

    Present address: Department of Psychology, University of Bristol, 8-10 Berkeley Square, Bs8 1HH, Bristol 8, England

Authors and Affiliations

  1. Department of Psychology, University of Bristol, 8-10 Berkeley Square, Bs8 1HH, Bristol 8, England

    J. Brown

  2. Department of Anatomy, University of Bristol, Bristol 8, England

    M. W. Brown & G. Horn

  3. Department of Anaesthetics, University of Bristol, Bristol 8, England

    J. B. Bowes

Authors
  1. J. Brown
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  2. Vivien Lewis
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  3. M. W. Brown
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  4. G. Horn
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  5. J. B. Bowes
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Additional information

Acknowledgments. The authors are grateful to Dr J. Hope and Dr D. Gosh for clinical assistance and to Dr T.V.A. Harry of John Wyeth and Brother Ltd, Dr W.H. Franklin of Roche Products Ltd and Professor J.B. Chappell for advice and discussion. We thank John Wyeth and Brother Ltd for financial support and for supplying lorazepam.

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Brown, J., Lewis, V., Brown, M.W. et al. Amnesic effects of intravenous diazepam and lorazepam. Experientia 34, 501–502 (1978). https://doi.org/10.1007/BF01935954

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  • DOI: https://doi.org/10.1007/BF01935954

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