Abstract
Chinese hamster cell mutants resistant to the lectins PHA, WGA, RIC, LCA, and CON A were previously grouped into 8–10 distinct phenotypes on the basis of their unique patterns of lectin resistance and lectin-binding properties. All but one of these classes of lectin-resistant (LecR) mutants behave recessively in somatic cell hybrids. One ricin-resistant class (\(\left( {Ric^{R_{II} } } \right)\) behaves dominantly. Test for complementation, by measuring the lectin-resistant properties of appropriate hybrids, show that seven distinct complementation groups can be delineated among the phenotypically recessive mutants.
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Stanley, P., Siminovitch, L. Complementation between mutants of CHO cells resistant to a variety of plant lectins. Somat Cell Mol Genet 3, 391–405 (1977). https://doi.org/10.1007/BF01542968
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DOI: https://doi.org/10.1007/BF01542968