Skip to main content
SpringerLink
Log in

Molecular and cellular markers for metastatic prostate cancer

  • Published:
Cancer and Metastasis Reviews Aims and scope Submit manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

References

  1. Boring CC, Squires TS, Tong T: Cancer Statistics, 1991. CA Cancer Journal of Clinicians 41: 19–36, 1991

    Google Scholar 

  2. Raghavan D: Non-hormone chemotherapy for prostate cancer: principles of treatment and application to the testing of new drugs. Seminars in Oncology 15: 371–389, 1988

    Google Scholar 

  3. Carter HB, Coffey D: Prostate cancer: The magnitude of the problem in the United States. In: Coffey D, Resnick M, Dorr Fet al. (eds) A Multidisciplinary Analysis of Controversies in the Management of Prostate Cancer. Plenum Press, New York, 1988, pp 1–9

    Google Scholar 

  4. Carter HB, Piantadosi S, Isaacs JT: Clinical evidence for and implications of the multistep development of prostate cancer. J Urol 143: 742–746, 1991

    Google Scholar 

  5. Vallancien G, Prapotnich D, Veillon B, Brisset JM, Andre-Bougaran J: Systematic prostatic biopsies in 100 men with no suspicion of cancer on digital rectal examination. J Urol 146: 1308–1312, 1991

    Google Scholar 

  6. Isaacs JT, Wake N, Coffey DS, Sandberg AA: Genetic instability coupled to clonal selection as a mechanism for tumor progression in the Dunning R-3327 rat prostatic adenocarcinoma system. Cancer Res 42: 2353–2361, 1982

    Google Scholar 

  7. Wake N, Isaacs J, Sandberg AA: Chromosomal changes associated with progression of the Dunning R-3327 rat prostatic adenocarcinoma system. Cancer Res 42: 4131–4142, 1982

    Google Scholar 

  8. Isaacs JT, Hukku B: Nonrandom involvement of chromosome 4 in the progression of rat prostatic cancer. The Prostate 13: 165–188, 1988

    Google Scholar 

  9. Frankfort DS, Chin JL, Englander LS, Greco WR, Pontes JE, Rustum YM: Relationship between DNA ploidy, glandular differentiation, and tumor spread in human prostate cancer. Cancer Res 45: 1418, 1985

    Google Scholar 

  10. McIntire TL, Murphy WM, Coon JS, Chandler RW, Schwartz D, Conway S, Weinstein RS: The prognostic value of DNA ploidy combined with histologic substaging for incidental carcinoma of the prostate gland. Amer J Clinical Path 89: 370–373, 1988

    Google Scholar 

  11. Winkler HZ, Rainwater LM, Myers RP, Farrow GM, Therneau TM, Zinche M, Lieber MM: Stage D1 prostatic adenocarcinoma: significance of nuclear DNA ploidy patterns studied by flow cytometry. Mayo Clin Proc 63: 103, 1988

    Google Scholar 

  12. Nativ O, Winkler HZ, Raz Y, Therneau TM, Farrow GM, Myers RP, Zinche H, Lieber MM: Stage C prostatic adenocarcinoma: flow cytometric nuclear DNA ploidy analysis. Mayo Clin Proc 64: 911, 1989

    Google Scholar 

  13. Johannson JE, Adami HO, Anderson SO, Bergstrom R, Krusemo UB, Kraaz W: Natural history of localized prostatic cancer. Lancet 2: 799, 1989

    Google Scholar 

  14. Montgomery BT, Nativ O, Blute ML, Farrow GM, Myers RP, Zincke H, Therneau TM, Lieber MM: Stage B prostate adenocarcinoma: flow cytometric nuclear DNA ploidy analysis. Arch Surg 125: 327–331, 1990

    Google Scholar 

  15. Adolfsson J, Rönström L, Hedlund P-O, Löwhagen T, Carstensen J, Tribukait B: The prognostic value of modal deoxyribonucleic acid in low grade, low stage untreated prostate cancer. J Urol 144: 1405–1407, 1990

    Google Scholar 

  16. Adolfsson J, Tribukait B: Evaluation of tumor progression by repeated fine needle biopsies in prostate adenocarcinoma: Modal deoxyribonucleic acid value and cytological differentiation. J Urol 144: 1408–1410, 1990

    Google Scholar 

  17. Brothman AR, Peehl DM, Patel AM, McNeal JE: Frequency and pattern of karyotypic abnormalities in human prostate cancer. Cancer Res 50: 3795–3803, 1990

    Google Scholar 

  18. Atkin NB, Baker MC: Chromosome study of five cancers of the prostate. Hum Genet 70: 359–364, 1985

    Google Scholar 

  19. Barbacid M:ras genes. Ann Rev Biochem 56: 779–827, 1987

    Google Scholar 

  20. Bos JL:ras oncogenes in human cancer: a review. Cancer Res 49: 4682–4689, 1989

    Google Scholar 

  21. Greenberg AH, Eagen SE, Wright JA: Oncogenes and metastatic progression. Invasion Metastasis 9: 360–378, 1989

    Google Scholar 

  22. Davenport EA, Drobes BL, Menke SL, Vaidya TB, Taparowsky EJ: Cooperation of oncogenes in the multistep transformation established fibroblasts in culture. Anticancer Res 8: 959–970, 1988

    Google Scholar 

  23. Thorgeirsson UP, Turpeeniemi-Hujanen T, Williams JE, Westin E, Heilman CAM, Talmadge JE, Liotta LA: NIH3T3 cells transfected with human tumor DNA containing activatedras oncogenes express the metastatic phenotype in nude mice. Mol Cell Biol 5: 259–262, 1985

    Google Scholar 

  24. Muschel RJ, Williams JE, Lowy DR, Liotta LA: Harveyras induction of metastatic potential depends upon oncogene activation and the type of recipient cells. Am J Path 121: 1–8, 1985

    Google Scholar 

  25. Cooke DB, Quarmby VE, Petrusz P, Mickey DD, Der CJ, Isaacs JT, French FS: Expression of ras proto-oncogens in the Dunning R-3327 rat prostatic adenocarcinoma system. The Prostate 13: 273–287, 1988

    Google Scholar 

  26. Bussemakers MJG, Isaacs JT, Debruyne FMJ, Van de Ven WJM, Schalken JA: Oncogene expression in prostate cancer. J Urol 9: 58–63, 1991

    Google Scholar 

  27. Treiger B, Isaacs JT: Expression of a transfected v-Harvey-ras oncogene in a Dunning rat prostate adenocarcinoma and the development of high metastatic ability. J Urol 140: 1580–1586, 1988

    Google Scholar 

  28. Schalken JA, Ebeling SB, Isaacs JT, Treiger B, Bussemakers MJG, deJong MEM, Van de Ven WJM: Down modulation of fibronectin messenger RNA in metastasizing rat prostatic cancer cells revealed by differential hybridization analysis. Cancer Res 48: 2042–2046, 1988

    Google Scholar 

  29. Partin AW, Isaacs JT, Treiger B, Coffey DS: Early cell motility changes associated with an increase in metastatic ability in rat prostatic cancer cells transfected with v-Harvey-ras oncogene. Cancer Res 48: 6050–6053, 1988

    Google Scholar 

  30. Ichikawa T, Schalken JA, Ichikawa Y, Steinberg GD, Isaacs JT: H-ras expression, genetic instability, and acquisition of metastatic ability by rat prostatic cancer cells following v-H-ras oncogene transfection. The Prostate 18: 163–172, 1991

    Google Scholar 

  31. Carter BS, Epstein JI, Isaacs WB:ras gene mutations in prostate cancer. Cancer Res 50: 6830–6832, 1990

    Google Scholar 

  32. Gumerlock PH, Poonamallee UR, Meyers FJ, deVere White RW: Activatedras alleles in human carcinoma of the prostate are rare. Cancer Res 51: 1632–1637, 1991

    Google Scholar 

  33. Viola M, Fromowitz F, Oravez S, Deb S, Finkel G, Lundy J, Hand P, Thor A, Schlom J: Expression ofras oncogene P21 in prostate cancer. N Engl J Med 314: 133–137, 1986

    Google Scholar 

  34. Sumiya H, Masai M, Akimoto S, Yatani K, Shimazaki J: Histochemical examination of the expression ofras p21 protein and R-1881-binding protein in human prostatic cancers. Eur J Cancer 26: 786–789, 1990

    Google Scholar 

  35. Bergerheim USR, Kunimi K, Collins VP, Ekman P: Deletion mapping of chromosomes 8, 10 and 16 in human prostatic carcinoma. Genes Chromosomes & Cancer 3: 215–220, 1991

    Google Scholar 

  36. Vogelstein B, Fearon ER, Hamilton ST, Kern SE, Preisinger AC, Leppert M, Nakamura Y, White R, Smits AMM, Bos JL: Genetic alterations during colorectal-tumor development. N Eng J Med 319: 525–532, 1988

    Google Scholar 

  37. Isaacs WB, Carter BS, Ewing CM: Wild-type p53 suppresses growth of human prostate cancer cells containing mutant p53 alleles. Cancer Res 51: 4716–4720, 1991

    Google Scholar 

  38. Takeichi M: Cadherins: molecular binding important in selective cell-cell adhesion. Annual Review of Biochemistry 59: 237–252, 1990

    Google Scholar 

  39. Frixen UH, Behrens J, Sachs M, Eberle G, Voss B, Warda A, Löchner D, Birchmeler W: E-cadherin-mediated cell-cell adhesion prevents invasiveness of human carcinoma cells. J Cell Biol 113: 173–185, 1991

    Google Scholar 

  40. Vleminckx K, Vakaet L Jr, Mareel M, Flers W: Genetic manipulation of e-cadherin expression by epithelial tumor cells reveals an invasion suppressor role. Cell 66: 107–119, 1991

    Google Scholar 

  41. Natt E, Magenis RE, Zimmer J, Mansouri A, Scherer G: Regional assignment of the human loci for uvomorulin (UVO) and chemotypinogen β (CTRβ) with the help of two overlapping detetions on the long arm of chromosome 16. Cytogenetic and Cell Genetic 50: 145–148, 1989

    Google Scholar 

  42. Bussemakers MJG, van Moorselaar RJA, Giroldi CA, Ichikawa I, Isaacs JT, Takeichi M, Debruyne FMJ, Schalken JA: Decreased expression of e-cadherin in the progression of rat prostatic cancer. Cancer Res 52: 2916–2922, 1992

    Google Scholar 

  43. Umbas R, Schalken JA, Aalders TW, Carter BS, Karthaus HFM, Schaatsma HE, Debruyne FMJ, Isaacs WB: Expression of the cellular adhesion molecular e-cadherin is reduced or absent in high grade prostate cancer. Cancer Res 1992, 52: 5104–5109, 1992

    Google Scholar 

  44. Passanitti A, Isaacs JT, Harvey JA, Adler SW, Cujdik TC, Long PU, Kleinmar HK: Stimulation of human prostatic carcinoma tumor growth in athymic mice and control of migration in culture by extracellular matrix. Int J Cancer 51: 318–324, 1992

    Google Scholar 

  45. Ichikawa T, Ichikawa Y, Isaacs JT: Genetic factors and suppression of metastatic ability of prostatic cancer. Cancer Res 51: 3788–3792, 1991

    Google Scholar 

  46. Ichikawa T, Ichikawa Y, Hawkins AL, Griffin CA, Isaacs WB, Oshimura M, Barrett JC, Isaacs JT: Localization of metastasis suppressor gene(s) for prostatic cancer to the short arm of human chromosome 11. Cancer Res 52: 3486–3490, 1992

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. The Johns Hopkins Oncology Center, The Department of Urology, The James Buchanan Brady Urological Institute, The Johns Hopkins University School of Medicine, 422 North Bond Street, 21231, Baltimore, MD, USA

    Carrie W. Rinker-Schaeffer, William B. Isaacs & Johns T. Isaacs

Authors
  1. Carrie W. Rinker-Schaeffer
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. William B. Isaacs
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Johns T. Isaacs
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Rinker-Schaeffer, C.W., Isaacs, W.B. & Isaacs, J.T. Molecular and cellular markers for metastatic prostate cancer. Cancer Metast Rev 12, 3–10 (1993). https://doi.org/10.1007/BF00689785

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF00689785

Key words

Search

Navigation