Abstract
The effects of Δ 9-THC, chlorpromazine and amylobarbitone on the labor division achieved by rats were studied. While the first two drugs in the doses of, respectively, 5.0 and 3.0 mg/kg, induced an inversion in the social pattern, amylobarbitone was ineffective at doses of 10.0 and 20.0 mg/kg; labor division of rats trained under a CRF was more sensitive to the drugs effects than that of animals under a VI schedule of reinforcement. Results were discussed in terms of a drug induced deconditioning effect without loss of motivation.
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With a fellowship from FundaÇÃo de Amparo à Pesquisa do Estado de SÃo Paulo (FAPESP).
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Masur, J., MÄrtz, R.M.W. & Carlini, E.A. The behavior of worker and non-worker rats under the influence of (−) δ9-trans-tetrahydrocannabinol, chlorpromazine and amylobarbitone. Psychopharmacologia 25, 57–68 (1972). https://doi.org/10.1007/BF00422617
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DOI: https://doi.org/10.1007/BF00422617