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A projection from the periaqueductal grey to the lateral reticular nucleus in the cat

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Summary

A projection from the periaqueductal grey (PAG) to the lateral reticular nucleus (NRL) in the cat was demonstrated by means of retrograde transport of the wheat germ agglutinin-horseradish peroxidase complex. The connection has its main origin ipsilaterally in the ventral part of the caudal PAG, but scanty projections from other parts of the PAG were also found. The neurons projecting to the NRL are of varying shapes and sizes, but most cells have a maximum diameter of less than 20 μm. The findings are discussed in relation to the other afferent and efferent connections of the NRL.

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References

  • Basbaum AI, Fields HL (1979) The origin of descending pathways in the dorsolateral funiculus of the spinal cord of the cat and rat: further studies on the anatomy of pain modulation. J Comp Neurol 187:513–532

    Google Scholar 

  • Basbaum AI, Clanton CH, Fields HL (1978) Three bulbospinal pathways from the rostral medulla of the cat. An autoradiographic study of pain modulating systems. J Comp Neurol 178:209–224

    Google Scholar 

  • Batton RR III, Jayaraman A, Ruggiero D, Carpenter MB (1977) Fastigial efferent projections in the monkey: an autoradiographic study. J Comp Neurol 174:281–306

    Google Scholar 

  • Brodal A (1943) The cerebellar connections of the nucleus reticularis lateralis (nucleus funiculi lateralis) in rabbit and cat. Experimental investigations. Acta Psychiatr (Kbh) 18:171–233

    Google Scholar 

  • Brodal A (1949) Spinal afferents to the lateral reticular nucleus of the medulla oblongata in the cat. An experimental study. J Comp Neurol 91:259–296

    Google Scholar 

  • Brodal P (1975) Demonstration of a somatopically organized projection onto the paramedian lobule and the anterior lobe from the lateral reticular nucleus: an experimental study with the horseradish peroxidase method. Brain Res 95:221–239

    Google Scholar 

  • Brodal P, Maršala J, Brodal A (1967) The cerebral cortical projection to the lateral reticular nucleus in the cat, with special reference to the sensorimotor cortical areas. Brain Res 6:252–274

    Google Scholar 

  • Brodal P, Dietrichs E, Bjaalie JG, Nordby T, Walberg F (1983) Is lectin-coupled horseradish peroxidase taken up and transported by undamaged as well as by damaged fibers in the central nervous system? Brain Res 278:1–9

    Google Scholar 

  • Castioglioni AJ, Gallaway MC, Coulter JD (1978) Spinal projections from the midbrain in the monkey. J Comp Neurol 178:329–346

    Google Scholar 

  • Cedarbaum JM, Aghajanian GK (1978) Afferent projections to the rat locus coeruleus as determined by a retrograde tracing technique. J Comp Neurol 178:1–16

    Google Scholar 

  • Chan-Palay V (1977) Cerebellar dentate nucleus: organization, cytology and transmitters. Springer, Berlin Heidelberg New York

    Google Scholar 

  • Chan-Palay V, Palay SL, Brown JT, Itallie C (1977) Sagittal organization of olivocerebellar and reticulocerebellar projections: autoradiographic studies with 35S-menthionine. Exp Brain Res 30:561–576

    Google Scholar 

  • Cohen C, Chambers WW, Sprague JM (1958) Experimental study of the efferent projections from the cerebellar nuclei to the brain stem of the cat. J Comp Neurol 109:233–259

    Google Scholar 

  • Corvaja N, Grofová I, Pompeiano O, Walberg F (1977) The lateral reticular nucleus in the cat. I. An experimental anatomical study of its spinal and supraspinal afferent connections. Neuroscience 2:537–553

    Google Scholar 

  • Courville J (1966) Rubrobulbar fibres to the facial nucleus and the lateral reticular nucleus (nucleus of the lateral funiculus). An experimental study in the cat with silver impregnation methods. Breain Res 1:317–337

    Google Scholar 

  • Courville J, Faraco-Cantin F, Marcon L (1983) Projections from the reticular formation of the medulla, the spinal trigeminal and lateral reticular nuclei to the inferior olive. Neuroscience 9:129–139

    Google Scholar 

  • Dietrichs E (1983a) Cerebellar nuclear afferents from the lateral reticular nucleus in the cat. Brain Res 288:320–324

    Google Scholar 

  • Dietrichs E (1983b) Cerebellar cortical afferents from the periaqueductal grey in the cat. Neurosci Lett 41:21–26

    Google Scholar 

  • Dietrichs E, Haines DE (1985) Observations on the cerebellohypothalamic projection, with comments on non-somatic cerebellar circuits. Arch Ital Biol 123:133–139

    Google Scholar 

  • Dietrichs E, Walberg F (1979) The cerebellar projection from the lateral reticular nucleus as studied with retrograde transport of horseradich peroxidase. Anat Embryol 155:273–290

    Google Scholar 

  • Dietrichs E, Haines DE, Qvist H (1985) Indirect hypothalamocerebellar pathway? Demonstration of hypothalamic efferents to the lateral reticular nucleus. Exp Brain Res (In press)

  • Edwards SB (1972) The ascending and descending projections of the red nucleus in the cat: an experimental study using an autoradiographic tracing method. Brain Res 48:45–63

    Google Scholar 

  • Eisenman LM (1982) The reticulocerebellar projection to the pyramis and copula pyramidis in the rat: an experimental study using retrograde transport of horseradish peroxidase. J Comp Neurol 210:30–36

    Google Scholar 

  • Eller TW, Chan-Palay V (1976) Afferents to the cerebellar lateral nucleus. Evidence from retrograde transport of horseradish peroxidase after pressure injections through micropipettes. J Comp Neurol 166:285–301

    Google Scholar 

  • Flumerfelt BA, Hrycyshyn AW, Kapogianis EM (1982) Spinal projections to the lateral reticular nucleus in the rat. Anat Embryol 165:345–359

    Google Scholar 

  • Gonatas NK, Harper C, Mizutani T, Gonatas JO (1979) Superior sensitivity of conjugates of horseradish peroxidase with wheat germ agglutinin for studies of retrograde axonal transport. J Histochem Cytochem 27:728–734

    Google Scholar 

  • Grofová I, Ottersen OP, Rinvik E (1978) Mesencephalic and diencephalic afferents to the superior colliculus and periaqueductal gray substance demonstrated by retrograde axonal transport of horseradish peroxidase in the cat. Brain Res 146:205–220

    Google Scholar 

  • Haines DE, Dietrichs E, Sowa TE (1984) Hypothalamo-cerebellar and cerebello-hypothalamic pathways: a review and hypothesis concerning cerebellar circuits which may influence autonomic centers and affective behavior. Brain Behav Evol 24:198–220

    Google Scholar 

  • Hinman A, Carpenter MB (1959) Efferent fiber projections of the red nucleus in the cat. J Comp Neurol 113:61–82

    Google Scholar 

  • Hrycyshyn AW, Flumerfelt BA (1981) A light microscopic investigation of the afferent connections of the lateral reticular nucleus in the cat. J Comp Neurol 197:447–502

    Google Scholar 

  • Hrycyshyn AW, Flumerfelt BA, Anderson WA (1982) A horseradish peroxidase study of the projection from the lateral reticular nucleus to the cerebellum in the rat. Anat Embryol 165:1–18

    Google Scholar 

  • Ito J, Sasa M, Matsuoka I, Takaori S (1982) Afferent projection from reticular nuclei, inferior olive and cerebellum to lateral vestibular nucleus of the cat as demonstrated by horseradish peroxidase. Brain Res 231:427–432

    Google Scholar 

  • Kawamura K, Brodal A, Hoddevik GH (1974) The projection of the superior colliculus onto the reticular formation of the brain stem. An experimental anatomical study in the cat. Exp Brain Res 19:1–19

    Google Scholar 

  • Kitai ST, DeFrance JF, Hatada K, Kennedy DT (1974) Electrophysiological properties of lateral reticular nucleus cells. II. Synaptic activation. Exp Brain Res 21:419–432

    Google Scholar 

  • Künzle H (1973) The topographic oprganization of spinal afferents to the lateral reticular nucleus of the cat. J Comp Neurol 149:103–116

    Google Scholar 

  • Künzle H (1975) Autoradiographic tracing of the cerebellar projections from the lateral reticular nucleus in the cat. Exp Brain Res 22:255–266

    Google Scholar 

  • Künzle H, Wiesendanger M (1974) Pyramidal connections to the lateral reticular nucleus in the cat: a degeneration study. Acta Anat (Basel) 88:105–114

    Google Scholar 

  • Kuypers HGJ (1958a) An anatomical analysis of corticobulbar connexions to the pons and lower brain stem in the cat. J Anat (Lond) 92:198–218

    Google Scholar 

  • Kuypers HGJ (1958b) Some projections from the pericentral cortex to the pons and lower brain stem in monkey and chimpanzee. J Comp Neurol 111:221–251

    Google Scholar 

  • Kuypers HGJ (1958c) Corticobulbar connexions to the pons and lower brain stem in man. An anatomical study. Brain 81:364–388

    Google Scholar 

  • Kuypers HGJ, Maisky VA (1975) Retrograde axonal transport of horseradish peroxidase from spinal cord to brain stem cell groups in the cat. Neurosci Lett 1:9–14

    Google Scholar 

  • Ladpli R, Brodal A (1968) Experimental studies of commissural and reticular formation projections from the vestibular nuclei in the cat. Brain Res 8:65–96

    Google Scholar 

  • Maisky VA, Kuypers H (1978) Studies of the supraspinal system neurons in the cat brain by the technique of retrograde axonal transport of horseradish peroxidase. Neirofiziologiia 10:115–124

    Google Scholar 

  • Mantyh PW (1983) Connections of midbrain periaqueductal gray in the monkey. II. Descending efferent projections. J Neurophysiol 49:582–594

    Google Scholar 

  • Mantyh PW, Peschanski M (1982) Spinal projections from the periaqueductal grey and dorsal raphe in the rat, cat and monkey. Neuroscience 7:2769–2776

    Google Scholar 

  • Marchand JE, Hagino N (1983) Afferents to the periaqueductal gray in the rat. A horseradish peroxidase study. Neuroscience 9:95–106

    Google Scholar 

  • Martin GF, Andrezik J, Crutcher K, Linauts M, Panneton M (1977) The lateral reticular nucleus of the opossum (Didelphis virginiana). II. Connections. J Comp Nerol 174:151–186

    Google Scholar 

  • Matsushita M, Ikeda M (1976) Projections from the lateral reticular nucleus to the cerebellar cortex and nuclei in the cat. Exp Brain Res 24:403–421

    Google Scholar 

  • Menétrey D, Roudier F, Besson JM (1983) Spinal neurons reaching the lateral reticular nucleus as studied in the rat by retrograde transport of horseradish peroxidase. J Comp Neurol 220:439–452

    Google Scholar 

  • Mesulam M-M (1978) Tetramethyl benzidine for horseradish peroxidase neurohistochemistry: a non-carcinogenic blue reaction-product with superior sensitivity for visualizing neural afferents and efferents. J Histochem Cytochem 26:106–117

    Google Scholar 

  • Mizuno N, Nakamura Y (1973) An electron microscope study of spinal afferents to the lateral reticular nucleus of the medulla oblongata in the cat. Brain Res 53:187–191

    Google Scholar 

  • Mizuno N, Mochizuki K, Akimoto C, Matsushima R, Nakamura Y (1973) Rubrobulbar projections in the rabbit. A light and electron microscopic study. J Comp Neurol 147:267–280

    Google Scholar 

  • Morin F, Kennedy DT, Gardner E (1966) Spinal afferents to the lateral reticular nucleus. I. A histological study. J Comp 126:511–522

    Google Scholar 

  • Payne JN (1983) Axonal branching in the projections from precerebellar nuclei to the lobulus soimplex of the rat's cerebellum investigated by retrograde fluorescent double labeling. J Comp Neurol 213:233–240

    Google Scholar 

  • Qvist H, Dietrichs E, Røste LS, Walberg F (1983) A projection from the raphe nuclei to the lateral reticular nucleus in the cat. Arch Ital Biol 121:249–257

    Google Scholar 

  • Qvist H, Dietrichs E, Walberg F (1984) An ipsilateral projection from the red nucleus to the lateral reticular nucleus in the cat. Anat Embryol 170:327–330

    Google Scholar 

  • Walberg F (1952) The lateral reticular nucleus of the medulla oblongata in mammals. J Comp Neurol 96:283–343

    Google Scholar 

  • Walberg F (1958a) Descending connectionsto the lateral reticular nucleus. An experimental study in the cat. J Comp Neurol 109:363–389

    Google Scholar 

  • Walberg F (1958b) On the termination of the rubrobulbar fibers. Experimental observations in the cat. J Comp Neurol 110:65–73

    Google Scholar 

  • Walberg F, Pompeiano O (1960) Fastigiofugal fibers to the lateral reticular nucleus. An experimental study in the cat. Exp Neurol 2:40–53

    Google Scholar 

  • Walberg F, Dietrichs E, Nordby T (1985) On the projections from the vestibular and perihypoglossal nuclei to the spinal trigeminal and lateral reticular nuclei in the cat. Brain Res 333:123–130

    Google Scholar 

  • Watkins LR, Griffin G, Leichnetz GR, Mayer DJ (1981) Identification and somatotopic organization of nuclei projecting via the dorsolateral funiculus in rats: a retrograde tracing study using HRP slow-release gels. Brain Res 223:237–255

    Google Scholar 

  • Zemlan FB, Kow L-M, Morrell JI, Pfaff DW (1979) Descending tracts of the lateral columns of the rat spinal cord: a study using the horseradish peroxidase and silver impregnation techniques. J Anat (Lond) 128:489–512

    Google Scholar 

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  1. Anatomical Institute, University of Oslo, Oslo, Norway

    Line Sveberg Røste, Espen Dietrichs & Fred Walberg

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  1. Line Sveberg Røste
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  2. Espen Dietrichs
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  3. Fred Walberg
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Røste, L.S., Dietrichs, E. & Walberg, F. A projection from the periaqueductal grey to the lateral reticular nucleus in the cat. Anat Embryol 172, 339–343 (1985). https://doi.org/10.1007/BF00318982

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