Summary
Intranuclear rodlets in chicken sympathetic and sensory neurons have been analyzed histochemically and found to be composed largely of protein with which small amounts of bound lipids or related compounds may be associated. These filamentous formations appear to contain neither DNA, RNA, free lipids (acidic or neutral), nor polysaccharides in amounts demonstrable by standard techniques. Among the amino acids comprising the rodlet protein are arginine, lysine, histidine, tyrosine, tryptophan, and possibly aspartic and glutamic acids; glycine and cysteine may also be present in small amounts.
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Supported by Research Grants NB-00858 from the NIH and 432 from NMSS to Dr. Murray, and a Post-doctoral Fellowship to Dr. Kim from the National Multiple Sclerosis Society.
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Kim, S.U., Masurovsky, E.B., Benitez, H.H. et al. Histochemical studies of the intranuclear rodlet in neurons of chicken sympathetic and sensory ganglia. Histochemie 24, 33–40 (1970). https://doi.org/10.1007/BF00310001
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DOI: https://doi.org/10.1007/BF00310001