Abstract
We have used specific single-stranded DNA probes cloned in M13 to analyze the kinetics of expression of 20 individual herpes simplex virus type 1 (HSV-1) transcripts, most of known function. The three α transcripts studied all differ in the details of their shut-off. There are at least three groups of β or early transcripts which differ both in the time of their maximum rate of synthesis and in the time of their shut off. Similarly late (βγ and γ) transcripts form a complex group all of which share the fact that their rates of synthesis reach a maximum at a time when β transcripts are being shut off.
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Zhang, YF., Wagner, E.K. The kinetics of expression of individual herpes simplex virus type 1 transcripts. VIRUS GENES 1, 49–60 (1987). https://doi.org/10.1007/BF00125685
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DOI: https://doi.org/10.1007/BF00125685