Skip to main content
SpringerLink
Log in

Pineal gland, photoperiodic responses, and puberty

  • Review Article
  • Published:
Journal of Endocrinological Investigation Aims and scope Submit manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

References

  1. Elliot J.A. Circadian rhythms and photoperiodic time measurement in mammals. Fed. Proc. 35: 2339, 1976.

    Google Scholar 

  2. Stetson M.H., Tate-Ostroff B. Hormonal regulation of the annual reproductive cycle of golden hamsters. Gen. Comp. Endocr. 329: 960, 1981.

    Google Scholar 

  3. Reiter R.J. Reproductive effects of the pineal gland and pineal indoles in the Syrian hamster and the albino rat. In: Reiter R.J. (Ed.), The pineal gland. Reproductive effects. CRC Press, Boca Raton, 1981, vol. 2, p. 45.

    CAS  Google Scholar 

  4. Moore R.Y. The innervation of the mammalian pineal gland. Prog. Reprod. Biol. 4: 1, 1978.

    CAS  Google Scholar 

  5. Hoffman K. Photoperiod, pineal, melatonin and reproduction in hamsters. Prog. Brain Res. 52: 397, 1979.

    Article  Google Scholar 

  6. Herbert J. The pineal gland and light-induced oestrus in ferrets. J. Endocrinol. 43: 625, 1969.

    Article  PubMed  CAS  Google Scholar 

  7. Cardinali D.P., Cuello A., Tramezzani J.H., Rosner J.M. Effects of pinealectomy on the testicular function of the adult male duck. Endocrinology 89: 1082, 1971.

    Article  PubMed  CAS  Google Scholar 

  8. Lincoln G.A., Short R.V. Seasonal breeding: Nature’s contraceptive. Recent Prog. Horm. Res. 36: 1, 1980.

    PubMed  CAS  Google Scholar 

  9. Barrell G.K., Lapwood K.R. Effects of modifying olfactory and pineal gland function on the seasonality of semen production, and plasma luteinizing hormone, testosterone and prolactin levels in rams. Anim. Reprod. Sci. 1: 229, 1979.

    Article  CAS  Google Scholar 

  10. Schultze B.A., Seal U.S., Platka E.D., Letellier M.A., Verme L.J., Ozoga J.J., Parsons J.A. The effect of pinealectomy on seasonal changes in prolactin secretion in the white-tailed deer (Odocoileus virginianus borealis). Endocrinology 108: 173, 1981.

    Article  Google Scholar 

  11. Ojeda S.R., Andrews W.W., Advis J.P., White S.S. Recent advances in the endocrinology of puberty. Endocr. Rev. 1: 228, 1980.

    Article  PubMed  CAS  Google Scholar 

  12. Relkin R. Relative efficacy of pinealectomy, hypothalamic and amygdaloid lesion in advancing puberty. Endocrinology 88: 415, 1971.

    Article  PubMed  CAS  Google Scholar 

  13. Dunaway J.E. Alteration in the timing of PMS-induced ovulation following pinealectomy. Neuroendocrinology 5: 281, 1969.

    Article  PubMed  CAS  Google Scholar 

  14. Nagle C.A., Cardinali D.P., Laborde N.P., Rosner J.M. Sex-dependent changes in rat retinal hydroxyindole-O-methyl transferase. Endocrinology 94: 294, 1974.

    Article  PubMed  CAS  Google Scholar 

  15. Faigon M.R., Cardinali D.P., Moguilevsky J.A. Pinealectomy advances the time of development of steroid feedback on luteinizing hormone release in immature female rats. Brain Res. 241: 366, 1982.

    Article  PubMed  CAS  Google Scholar 

  16. Cardinali D.P. Melatonin. A mammalian pineal hormone. Endocr. Rev. 2: 327, 1981.

    Article  PubMed  CAS  Google Scholar 

  17. Quay W.B. General biochemistry of the pineal gland of mammals. In: Reiter R.J. (Ed.), The pineal gland. Anatomy and biochemistry CRC Press, Boea Raton, 1981, vol. 1, p. 173.

    CAS  Google Scholar 

  18. Klein D.C., Auerbach D.A., Namboodiri M.A.A., Wheler G.H.T. Indole metabolism in the mammalian pineal gland. In: Reiter R.J. (Ed.), The pineal gland. Anatomy and biochemistry. CRC Press, Boca Raton, 1981, vol. 1, p. 199.

    CAS  Google Scholar 

  19. Brownstein M., Axelrod J. Pineal gland: 24-hour rhythm in norepinephrine turnover. Science 48: 163, 1974.

    Article  Google Scholar 

  20. Cardinali D.P., Ritta M.N. The role of prostaglandins in neuroendocrine functions. Studies in the pineal gland and the hypothalamus. Neuroendocrinology 36: 152, 1983.

    Article  PubMed  CAS  Google Scholar 

  21. Cardinali D.P. Hormone effects on the pineal gland. In: Reiter R.J. (Ed.), The pineal gland. Anatomy and Biochemistry. CRC Press, Boca Raton, 1981, vol. 1, p. 243.

    CAS  Google Scholar 

  22. Arendt J. Melatonin assays in body fluid. J. Neural Transm. (Suppl). 13: 265, 1978.

    CAS  Google Scholar 

  23. Birau N. Melatonin in human serum: progress in screening investigation and clinic. Adv. Biosci. 29: 297, 1981.

    CAS  Google Scholar 

  24. Penny R. Melatonin excretion in normal males and females: increase during puberty. Metabolism 31: 816, 1982.

    Article  PubMed  CAS  Google Scholar 

  25. Cardinali D.P. Molecular mechanisms of neuroendocrine integration in the central nervous system. An approach through the study of the pineal gland and its innervating sympathetic pathway. Psychoneuroendocrinology 8: 3, 1983.

    Article  PubMed  CAS  Google Scholar 

  26. Moguilevsky J.A., Faigon M.R., Scacchi P., Cardinali D.P. Effect of melatonin and superior cervical ganglionectomy on luteinizing hormone release induced by estradiol-progesterone in castrated rats. Neuroendocrinology 29: 163, 1979.

    Article  PubMed  CAS  Google Scholar 

  27. Cardinali D.P., Ritta M.N., Fuentes A.M., Gimeno M.F., Gimeno A.L. Prostaglandin E release by rat medial basal hypothalamus in vitro. Inhibition by melatonin at submicromolar concentrations. Eur. J. Pharmacol. 67: 151, 1980.

    Article  PubMed  CAS  Google Scholar 

  28. Vacas M.I., Keller Sarmiento M.J., Cardinali D.P. Melatonin increases cGMP and decreases cAMP levels in rat medial basal hypothalamus in vitro. Brain Res. 225: 207, 1981.

    Article  PubMed  CAS  Google Scholar 

  29. Cardinali D.P., Vacas M.I., Boyer E.E. Specific binding of melatonin in bovine brain. Endocrinology 105: 437, 1979.

    Article  PubMed  CAS  Google Scholar 

  30. Martini J.E., Sattler C. Developmental loss of the acute inhibitory effect of melatonin on the in vitro pituitary LH and FSH responses to LH-releasing hormone. Endocrinology 105: 1007, 1979.

    Article  Google Scholar 

  31. Leach C.M., Reynoldson J.A., Thornburn G.D. Release of E prostaglandins into the cerebrospinal fluid and its inhibition by melatonin after cervical stimulation in the rabbit. Endocrinology 110: 1320, 1982.

    Article  PubMed  CAS  Google Scholar 

  32. Tamarkin L, Westrom W.K., Hamill A.I., Goldman B.D. Effect of melatonin on the reproductive system of male and female Syrian hamsters: a diurnal rhythm in sensitivity to melatonin. Endocrinology 99: 1534, 1976.

    Article  PubMed  CAS  Google Scholar 

  33. Vacas M.I., Cardinali D.P. Diurnal changes in melatonin binding sites of hamster and rat brain. Correlation with neuroendocrine responsiveness to melatonin. Neurosci. Lett. 15: 259, 1979.

    Article  PubMed  CAS  Google Scholar 

  34. Ebels I., Benson B. A survey of the evidence that unidentified pineal substance affect the reproductive system in mammals. Prog. Reprod. Biol. 4: 51, 1978.

    CAS  Google Scholar 

  35. Soffer L.J., Fogel M., Rudavsky A.Z. Gonadotropin-inhibiting substance. Isr. J. Med. Sci. 1: 1267, 1965.

    CAS  Google Scholar 

  36. Ota M., Hsieh K.S., Obara K. Absence of gonadotropin-inhibiting substance in the urine of pinealectomized rats. Endocrinology 88: 816, 1971.

    Article  PubMed  CAS  Google Scholar 

  37. Harris J.C., Knigge K.M. Disappearance of a urinary antigonadotrophin following HCG administration in Prader-Willi syndrome. In: Reiter R.J. (Ed.), Pineal and its hormone. Alan R. Liss, New York, 1982, p. 273.

    Google Scholar 

  38. Vaughan M.K. Arginine vasotocin and vertebrate reproduction. In: Reiter R.J. (Ed.), The pineal gland. Reproductive effects. CRC Press, Boca Raton, 1981, vol. 2, p. 125.

    CAS  Google Scholar 

  39. Carletti B., Kehyayan E., Fraschini F. Remarkable seasonal variation of urinary gonadotrophin excretion in young.girls. Experientia 20: 383, 1964.

    Article  PubMed  CAS  Google Scholar 

  40. Shakin A. The seasonal rhythm of menarche in girls attending. schools in Baghdag. Ann. Hum. Biol. 1: 95, 1974.

    Article  Google Scholar 

  41. Marshall W.A., Swan A.V. Seasonal variations in growth rate of normal and blind children. Hum. Biol. 43: 502, 1971.

    PubMed  CAS  Google Scholar 

  42. Borit A. History of tumors of the pineal region. Am. J. Surg. Pathol. 5: 613, 1981.

    Article  PubMed  CAS  Google Scholar 

  43. Vaughan G.M., Reiter R.J. Evidence for a pineal-gonad relationship in the human. Prog. Reprod. Biol. 4: 191, 1978.

    CAS  Google Scholar 

  44. Skalar C.A., Conte F.A., Kaplan S.L., Grumbach M.M. Human chorionic gonadotropin-secreting pineal tumor: relation to pathogenesis and sex limitation of sexual precocity. J. Clin. Endocrinol. Metab. 53: 656, 1981.

    Article  Google Scholar 

  45. Barber S.G., Smith J.A., Hughes P.C. Melatonin as a tumorous marker in a patient with pineal tumor. Br. Med. J. 2: 238, 1978.

    Article  Google Scholar 

  46. Silman R.E., Leone R.M., Hooper R.J.L. Melatonin, the pineal gland and human puberty. Nature 282: 301, 1979.

    Article  PubMed  CAS  Google Scholar 

  47. Ehrenkranz J.R.L., Tamarkin L., Comite F., Johnsonbaugh R.E., Bybee D.E., Loriaux D.L., Cutler G.B. Daily rhythm of plasma melatonin in normal and precocious puberty. J. Clin. Endocrinol. Metab. 55: 307, 1982.

    Article  PubMed  CAS  Google Scholar 

  48. Lenko H.L., Lang U., Aubert M.L., Paunier L., Sizonenko P.C. Hormonal changes in puberty. VII. Lack of variation of daytime plasma melatonin. J. Clin. Endocrinol. Metab. 54: 1056, 1982.

    Article  PubMed  CAS  Google Scholar 

  49. Gupta D., Riedel L., Frick H.J., Attanasio A., Ranke M. Circulating melatonin in children: in relation to puberty, endocrine disorders, functional tests and racial origin. Neuroendocr. Lett. 4: 189, 1982.

    Google Scholar 

  50. Cohen H.N., Hay I.D., Annesley T.M., Beastall G.H., Wallace A.M., Spooner R., Thomson J.A., Eastwoold P., Klee G.G. Serum immunoreactive melatonin in boys with delayed puberty. Clin. Endocrinol. (Oxf.) 17: 517, 1982.

    Article  CAS  Google Scholar 

  51. Tamarkin L, Abastillas P., Chen H.C., McNemar A., Sidbury J.B. The daily profile of plasma melatonin in obese and Prader-Willi syndrome children. J. Clin. Endocrinol. Metab. 55: 491, 1982.

    Article  PubMed  CAS  Google Scholar 

  52. Févre M., Segal T., Marks J.F., Boyar R.M. LH and melatonin secretion patterns in pubertal boys. J. Clin. Endocrinol. Metab. 47: 1383, 1978.

    Article  PubMed  Google Scholar 

  53. Lemaitre B.J., Boville J., Hartmann L. Variation of urinary melatonin excretion in humans during the first 30 years of life. Clin. Chim. Acta 110: 77, 1981.

    Article  PubMed  CAS  Google Scholar 

  54. Tetsuo M., Poth M., Markey S.P. Melatonin metabolite excretion during childhood and puberty. J. Clin. Endocrinol. Metab. 55: 311, 1982.

    Article  PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Centro de Estudios Farmacologicos y de Principios Naturales (CEFAPRIN), Serrano 665/669, 1414, Buenos Aires, Argentina

    D. P. Cardinali & M. I. Vacas

Authors
  1. D. P. Cardinali
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. M. I. Vacas
    View author publications

    You can also search for this author in PubMed Google Scholar

Additional information

Studies in authors’ laboratory were supported by grants from the Consejo Nacional de Investigaciones Cientificas y Técnicas (CONICET) (no. 6638) and the “Fundacion Alberto J. Roemmers”, Argentina. The authors are Established Investigators, CONICET, Argentina

Rights and permissions

Reprints and permissions

About this article

Cite this article

Cardinali, D.P., Vacas, M.I. Pineal gland, photoperiodic responses, and puberty. J Endocrinol Invest 7, 157–166 (1984). https://doi.org/10.1007/BF03348408

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF03348408

Key-words

Search

Navigation