Abstract
The basic characteristics of the flow-through cell apparatus (USP Apparatus IV) including the assembly and open/closed configuration of the apparatus have been described. The relative advantages of the flow-through cell apparatus over other release setups have been summarized. Finally, potential applications of this setup are presented.
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USP 26-NF21. The United States Pharmacopoeia-The National Formulary. Rockville MD, 20852, The United States Pharmacopoeial Convention, Inc., 2003.
H. Moller, Pharm. Ind. 45 (1983) 617.
S.N. Bhattachar, J.A. Wesley, A. Fioritto, P.J. Martin, S.R. Babu, Int. J. Pharm.236 (2002) 135.
A. Hodson, K.A. Wilkinson, Disso. Tech. 12 (2005) 44.
E. Nicolaides, M. Symillides, J.B. Dressman, C. Reppas, Pharm. Res. 18 (2001) 380.
N. Ozdemir, S. Ordu, Y. Ozkan, Drug Dev. Ind. Pharm. 26 (2000) 857.
H. Jack, K. Ali, K. Vivian, Z. Peter, C. Nina, Disso. Tech. 12 (2005) 6.
V.H. Sunesen, B.L. Pedersen, H.G. Kristensen, A. Mullertz, Eur. J. Pharm. Sci. 24 (2005) 305.
L. Bonlokke, L. Hovgaard, H.G. Kristensen, L. Knutson, H. Lennernas, Eur. J. Pharm. Sci. 12 (2001) 239.
L. Kalantzi, E. Nicolaides, R.C. Page, G.A. Digenis, C. Reppas, Prediction of the Average Plasma Profile after Oral Administration of Cross-Linked Gelatin Capsules of Amoxicillin, Poster Presentation, International Symposium on Scientific and Regulatory Aspects of Dissolution and Bioeuivalence, Athens, 2002.
L.H. Emara, B.S. El-Menshawi, M.Y. Estefan, Drug Dev. Ind. Pharm. 26 (2000) 243.
N. Fotaki, M. Symillides, C. Reppas, Eur. J. Pharm. Sci. 24 (2005) 115.
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Singh, I., Aboul-Enein, H.Y. Advantages of USP Apparatus IV (flow-through cell apparatus) in dissolution studies. JICS 3, 220–222 (2006). https://doi.org/10.1007/BF03247211
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DOI: https://doi.org/10.1007/BF03247211