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The scintigraphic appearance of childhood moyamoya disease on cerebral perfusion imaging

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Abstract

Objective

This study was performed to evaluate the role of single photon emission computed tomography (SPECT) perfusion imaging in the evaluation of patients with moyamoya disease.

Materials and methods

Five patients (four female, one male) were studied utilizing iodine-123 iodoam-phetamine or technetium-99m hexamethylpropyleneamine oxime SPECT. The data were reconstructed into axial, coronal and sagittal sections for review, and compared with CT, MR and/or angiographic images.

Results

All five patients had significant perfusion defects. These areas of vascular compromise were seen to cross normal vascular territories, and were greater in number and extent than seen on anatomic sectional imaging.

Conclusion

Patients with moya-moya disease have a recognizable pattern of scintigraphic perfusion deficits which should be identified by pediatric imaging physicians. SPECT perfusion studies should be performed in conjunction with other imaging modalities (CT, MR or angiography).

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Authors and Affiliations

  1. Department of Radiology, Childrens Hospital Los Angeles, 4650 Sunset Boulevard, 90027, Los Angeles, CA, USA

    J. H. Miller

  2. Department of Surgery, Childrens Hospital Los Angeles, USA

    C. Raffelel

  3. University of Southern California School of Medicine, Los Angeles, USA

    J. H. Miller & A. Khonsary

Authors
  1. J. H. Miller
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  2. C. Raffelel
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  3. A. Khonsary
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Miller, J.H., Raffelel, C. & Khonsary, A. The scintigraphic appearance of childhood moyamoya disease on cerebral perfusion imaging. Pediatr Radiol 26, 833–838 (1996). https://doi.org/10.1007/BF03178033

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  • DOI: https://doi.org/10.1007/BF03178033

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