Abstract
An attempt has been made to assessin vitro cytotoxicity of an endophytic fungus fromNothapodytes foetida. Various human cancer cell lines (liver HEP-2, lung A-549, ovary OVAR-5, prostate PC-3, cervix Hela, colon HCT-15, oral cell line KB, CNS SNB-78, were used.In vitro cytotoxicity of camptothecin (CPT) isolated from the fungus was done where OVAR-5 cell line showed maximum inhibition and HEP-2 cell line was least sensitive with this compound.In vitro cytotoxicity of fractions/extracts from endophyte was carried out where ethyl acetate fraction showed sufficient growth inhibition against all the cell lines.
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Rehman, S., Shawl, A.S., Sultana, S. et al. In vitro cytotoxicity of an endophytic fungus isolated fromNothapodytes foetida . Ann. Microbiol. 59, 157–161 (2009). https://doi.org/10.1007/BF03175614
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DOI: https://doi.org/10.1007/BF03175614