Abstract
Farnesol as a quorum-sensing molecule secreted byCandida albicans prevents the yeast to mycelium conversion and causes the cultures to grow as activity budding yeasts, but has no effect on cellular growth rates. A growth inhibitory effect onPenicillium expansum was found in our study by addition of exogenous farnesol to cultures, just like which was reported onAspergillus nidulans. The result implied that farnesol triggered apoptosis-like phenotype inP. expansum, including nuclear condensation, DNA fragmentation and the integrity of plasma membranes. Besides, farnesol induced the morphology of hypha changes when it was exposed toP. expansum spores suspension.
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Liu, P., Deng, B., Long, CA. et al. Effect of farnesol on morphogenesis in the fungal pathogenPenicillium expansum . Ann. Microbiol. 59, 33–38 (2009). https://doi.org/10.1007/BF03175595
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DOI: https://doi.org/10.1007/BF03175595