Summary
The nuclear oxidation of chrysin and tectochrysin has been successfully effected using potassium persulphate. The first yields norwogonin and the second the 7-methyl-ether now named isowogonin. The method of oxidative demethylation of the 5- and 8-positions has also been employed for the preparation of isowogonin from 5∶7∶8-trimethoxy-flavone.
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References
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Rao, K.V., Rao, K.V. & Seshadri, T.R. Nuclear oxidation in the flavone series. Proc. Indian Acad. Sci. (Math. Sci.) 25, 427 (1947). https://doi.org/10.1007/BF03171419
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DOI: https://doi.org/10.1007/BF03171419