Abstract
A total of 88 cases of clinically suspected nonneoplastic lymphadenopathy of cervical group of lymph nodes were studied for immunoglobulin pattern. Diagnosis was clinched by various investigations like ERS. Mantoux test, Chest X ray etc and fine needle aspiration cytology or open biopsy tmd thus catgorised to three groups e.g. tuberculous lymphadenitis (Group I) — 64 cases; chronic nonspecific lymphadenitis (Group II) — 18 cases; and 6 cases, of submandibular and submental salivary gland lesions (Grtmp III) which served as control.
Clinical presentations were mainly cervical lymphadenopathy associated with fever, loss of weight, malaise and lethergy. ESR was high in most of the cases. Mantoux test was positive in majority of the cases including few of the control group.
IgG and IgM levels were higher than normal in most of the cases of all the three study groups. But IgA level was normal in majority of the cases including the control group which were essentially salivary gland lesions.
Thus it appeard that the augmented humoral and cellular immune response in all the three groups are immunologically significant but of no diagnostic value.
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Banerjee, S., Basu, K., Sinha, S.K. et al. Immunoglobulin pattern in tuberculous lymphadenitis of cervical lymph nodes. Indian J Otolaryngol Head Neck Surg 45, 136–139 (1993). https://doi.org/10.1007/BF03054714
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DOI: https://doi.org/10.1007/BF03054714