Summary
1. Frog’s heart (Rana tigrina) contains more noradrenaline than adrenaline.
2. Spontaneously beating frog’s heart releases adrenaline and noradrenaline.
3. Stimulation of the sympathetic nerves releases adrenaline as well as noradrenaline.
4. After fatigue of the sympathetic nerves by maximal stimulation for one hour, direct electrical stimulation releases adrenaline and noradrenaline in amounts greater than can be released by nervous stimulation. These hormones therefore can originate from muscle cells.
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Singh, I., Singh, S.I., Malhotra, C.L. et al. Source of adrenaline and noradrenaline in the frog’s heart on stimulation of the sympathetic nerves. Proc. Indian Acad. Sci. 52, 33–42 (1960). https://doi.org/10.1007/BF03050050
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DOI: https://doi.org/10.1007/BF03050050