Skip to main content
SpringerLink
Log in

Ribosome binding to endoplasmic reticulum

  • Published:
Cell Biophysics Aims and scope Submit manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

References

  1. Palade, G. (1975) Intracellular aspects of the process of protein synthesis.Science 189, 347–359.

    Article  PubMed  CAS  Google Scholar 

  2. Blobel, G. and Dobberstein, B. (1975) Transfer of proteins across membranes. I. Presence of proteolytically processed and unprocessed nascent immunoglobulin light chains on membrane-bound ribosomes of murine myeloma.J. Cell Biol. 67, 835–851.

    Article  PubMed  CAS  Google Scholar 

  3. Milstein, C., Brownlee, G. G., Harrison, T. M., and Mathews, M. B. (1972) A possible precursor of immunoglobulin light chains.Nature New Biol. 239, 117–120.

    Article  PubMed  CAS  Google Scholar 

  4. Blobel, G. and Sabatini, D. D. (1971) Ribosome-membrane interaction in eukaryotic cells, inBiomembranes vol. 2 (L. A. Manson, ed.), Plenum, New York, pp. 193–195.

    Google Scholar 

  5. Walter, P., Ibrahimi, I., and Blobel, G. (1981) Translocation of proteins across the endoplasmic reticulum. I. Signal recognition particle (SRP) binds to in vitro assembled polysomes synthesizing secretory proteins.J. Cell Biol. 941, 545–550.

    Article  Google Scholar 

  6. Meyer, D. I., Krause, E., and Dobberstein, B. (1982) Secretory protein translocation across membranes: the role of the “docking protein.”Nature 297, 647–650.

    Article  PubMed  CAS  Google Scholar 

  7. Gilmore, R., Walter, P., and Blobel, G. (1982) Protein translocation across the endoplasmic reticulum. I. Detection in the microsomal membrane of a receptor for the signal recognition particle.J. Cell Biol. 95, 470–477.

    Article  PubMed  CAS  Google Scholar 

  8. Borgese, N., Mok, W., Kreibich, G., and Sabatini, D. D. (1974) Ribosome-membrane interaction: in vitro binding of ribosomes to microsomal membranes.J. Mol. Biol. 88, 559–580.

    Article  PubMed  CAS  Google Scholar 

  9. Hortsch, M., Avossa, D., and Meyer, D. I. (1986) Characterization of secretory protein translocation: Ribosome-membrane interaction in endoplasmic reticulum.J. Cell Biol. 103, 241–253.

    Article  PubMed  CAS  Google Scholar 

  10. Savitz, A. J. and Meyer, D. I. (1990) Identification of a ribosome receptor in the rough endoplasmic reticulum.Nature 346, 540–544.

    Article  PubMed  CAS  Google Scholar 

  11. Deshaies, R. J. and Schekman, R. (1987) A yeast mutant defective at an early stage in import of secretory protein precursors into the endoplasmic reticulum.J. Cell Biol. 105, 633–645.

    Article  PubMed  CAS  Google Scholar 

  12. Toyn, J., Hibbs, A. R., Sanz, P., Crowe, J., and Meyer, D. I. (1988)In vivo andin vitro analysis ofptl 1,a yeastis mutant with a membrane-associated defect in protein translocation.EMBO J. 7, 4347–4353.

    PubMed  CAS  Google Scholar 

  13. Rothblatt, J. A., Deshaies, R. J., Sanders, S. L., Daum, G., and Schekman, R. (1989) Multiple genes are required for proper insertion of secretory proteins into the endoplasmic reticulum in yeast.J. Cell Biol. 109, 2641–2652.

    Article  PubMed  CAS  Google Scholar 

  14. Rothblatt, J. A. and Meyer, D. I. (1986) Secretion in yeast: Reconstitution of the translocation and glycosylation of α-factor and invertase in a homologous cell-free system.Cell 44, 619–628.

    Article  PubMed  CAS  Google Scholar 

  15. Hansen, W., Garcia, P. D., and Walter, P. (1986) In vitro protein translocation across the yeast endoplasmic reticulum: ATP-dependent posttranslational translocation of the prepro-alpha-factor.Cell 45, 397–406.

    Article  PubMed  CAS  Google Scholar 

  16. Waters, M. G. and Blobel, G. (1986) Secretory protein translocation in a yeast cell-free system can occur posttranslationally and requires ATP hydrolysis.J. Cell Biol. 102, 1543–1550.

    Article  PubMed  CAS  Google Scholar 

  17. Sanderson, C. M., Crowe, J. S., and Meyer, D. I. (1990) Protein retention in yeast rough endoplasmic reticulum: Expression and assembly of human ribophorin I.J. Cell Biol. 111, 2861–2870.

    Article  PubMed  CAS  Google Scholar 

  18. Rothblatt, J. A. and Meyer, D. I. (1986) Secretion in yeast: Translocation and glycosylation of prepro-α-factor in vitro can occur via an ATP-dependent posttranslational mechanism.EMBO J. 5, 1031–1036.

    PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Biological Chemistry, UCLA School of Medicine, 90024, Los Angeles, CA

    Christopher M. Sanderson, Adam J. Savitz & David I. Meyer

  2. The Molecular Biology Institute, University of California, 90024, Los Angeles, CA

    Christopher M. Sanderson, Adam J. Savitz & David I. Meyer

Authors
  1. Christopher M. Sanderson
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Adam J. Savitz
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. David I. Meyer
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Sanderson, C.M., Savitz, A.J. & Meyer, D.I. Ribosome binding to endoplasmic reticulum. Cell Biophysics 19, 17–23 (1991). https://doi.org/10.1007/BF02989875

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF02989875

Keywords

Search

Navigation