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Dictyostelium caveatum mutants selected for a nystatin-resistant phenotype are cross-resistant to pisatin and other isoflavonoid phytoalexins

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Abstract

Cellular slime mould amoebae can be induced to become resistant to an otherwise inhibitory concentration of pisatin, an isoflavonoid phytoalexin of pea, if they are first treated with a subinhibitory concentration. We report here the serendipitous isolation of pisatin-resistant mutants in the cellular slime mouldDictyostelium caveatum. However, the pisatin resistance phenotype of the mutants appears to have a different basis than the inducible pisatin resistance phenotype of the wild type.

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Authors and Affiliations

  1. Centre for Cellular and Molecular Biology, 500007, Hyderabad, India

    Durgadas P. Kasbekar & Bhavani T. Prasanna

  2. Indian Institute of Chemical Technology, 500 007, Hyderabad, India

    M. Vairamani

Authors
  1. Durgadas P. Kasbekar
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  2. Bhavani T. Prasanna
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  3. M. Vairamani
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Correspondence to Durgadas P. Kasbekar.

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Kasbekar, D.P., Prasanna, B.T. & Vairamani, M. Dictyostelium caveatum mutants selected for a nystatin-resistant phenotype are cross-resistant to pisatin and other isoflavonoid phytoalexins. J. Genet. 77, 37–40 (1998). https://doi.org/10.1007/BF02933039

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  • DOI: https://doi.org/10.1007/BF02933039

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