Summary
Using histochemical technique, the effects of radiofrequency catheter ablation (RFCA) on the activities of LDH, SDH, CCO, and Ca++-ATPase of guinea-pig ventricular myocytes were examined. The histological changes were observed for comparison. Radiofrequency energy (500 kHz) delivered was 20 WX 10 s. The results were as follows: RFCA resulted in significant impairments in all the four kinds of enzymes but without statistical differences in the areas involved in this energy level. No statistically significant difference was found between the ranges of enzymatic damages and areas of pathological lesions. These findings showed a consistency in areas of the histological and histochemical lesions resulted from RFCA.
Similar content being viewed by others
References
Huang S K S, Graham A R, Wharton K. Radiofrequency catheter ablation of the left and right ventricles: Anatomic and electrophysiologic observation. PACE, 1988, 11: 449
Hindricks G, Borggreft M. Short and long term complications of catheter ablation using radiofrequency energy-observations in 192 consecutive patients. J Am Coll Cardial, 1992, 19: 184A (abstract)
Newman D, Evans G T, Scheinman M. Catheter ablation of Cardiac arrhythmias. Curr Probl Cardiol, 1989, March: 123
Huang S K, Bharati S, Graham A Ret al. closed chest catheter desiccation of the atrioventricular junction using radiofrequency energy-a new method of catheter ablation. J Am Coll Cardiol, 1987, 9: 349
Huang S K. Advances in applications of radiofrequency current to catheter ablation therapy. PACE, 1991, 14(1): 28
Huang S K, Bharati S, Lev Met al. electrophysiologic and histologic observations of chronic atrioventricular block induced by closed-chest catheter desiccation with radiofrequency energy. PACES 1987, 10: 805
Henry. Principles and techniques of histochemistry, Boston: Little, Brown and Company (Inc), 1980. 298, 225, 302, 304
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Yanggan, W., Zaiying, L. & Xikai, X. The effects of radiofrequency catheter ablation on the metabolic enzymes and Ca++-ATPase of myocytes. Journal of Tongji Medical University 16, 18–19 (1996). https://doi.org/10.1007/BF02889037
Received:
Issue Date:
DOI: https://doi.org/10.1007/BF02889037