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Clinical implication of serum sIL-2R levels in ovarian cancer

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Summary

The levels of serum soluble interleukin-2 receptor (sIL-2R) of 36 patients with ovarian cancer, 34 with benign gynecological tumors and 31 blood donors were measured by ELISA. Compared to those of benign and normal controls, serum levels of sIL-2R in patients with ovarian cancer elevated significantly (P <0.01). Serum sIL-2R levels were likely related to types, clinical stage or histological grading of ovarian cancer. We were led to conclude that serum sIL-2R level may reflect the status of the immune system and the disease severity in patients with ovarian cancer. Its value as a marker for monitoring treatment and prognosis needs further studies.

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Authors and Affiliations

  1. Department of Obstetrics and Gynecology, Tongji Hospital, Tongji Medical Univrrsity, 430030, Wuhan

    Wang Shixuan M.D., Ph.D., Cai Guiru & Lu Yunping

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  1. Wang Shixuan M.D., Ph.D.
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  2. Cai Guiru
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  3. Lu Yunping
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Shixuan, W., Guiru, C. & Yunping, L. Clinical implication of serum sIL-2R levels in ovarian cancer. Current Medical Science 18, 126–128 (1998). https://doi.org/10.1007/BF02888484

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  • DOI: https://doi.org/10.1007/BF02888484

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